Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Meloxicam
Drug ID BADD_D01374
Description Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve various types of pain, including pain caused by musculoskeletal conditions, osteoarthritis, and rheumatoid arthritis.[A190189] With a longer half-life than most other NSAIDS, it is a favorable option for those who require once-daily dosing. Meloxicam is available in oral, transdermal, and intravenous formulations. It is a preferential COX-2 inhibitor, purportedly reducing the risk of adverse gastrointestinal tract effects, however, this is a topic of controversy.[A190198,A190201]
Indications and Usage For symptomatic treatment of arthritis and osteoarthritis.
Marketing Status Prescription; Discontinued
ATC Code M01AC06
DrugBank ID DB00814
KEGG ID D00969
MeSH ID D000077239
PubChem ID 54677470
TTD Drug ID D0G7FJ
NDC Product Code 61919-469; 38779-2746; 67296-1317; 29300-125; 68788-7904; 63629-2020; 71610-583; 0615-8124; 70518-1828; 65841-051; 43063-396; 43063-401; 72865-138; 69344-205; 80425-0043; 61919-434; 71610-580; 68071-4987; 71610-544; 42708-093; 65862-097; 70518-3023; 43063-395; 50090-5339; 51552-1377; 50436-1125; 17373-1157; 56125-750; 70954-077; 70859-007; 69344-206; 17373-1158; 72969-045; 60760-419; 60760-448; 43353-979; 80425-0045; 51869-0008; 76282-153; 65841-050; 70934-010; 60592-994; 72865-137; 59349-0003; 53002-1537; 50090-5861; 0615-8040; 53747-006; 68071-1919; 53069-0790; 50090-0986; 67296-1817; 50436-1124; 68071-3030; 71335-0406; 51407-610; 45865-360; 68382-050; 35356-808; 69097-159; 67296-0583; 54458-964; 50090-5340; 68180-502; 51407-611; 61442-126; 50090-0985; 61442-127; 71205-923; 43353-127; 68382-051; 80425-0041; 71518-001; 67296-0823; 68225-112; 16571-776; 50268-526; 51869-0007; 52119-003; 71610-542; 76282-152; 55289-618; 67296-1250; 49452-4402; 71335-1888; 68981-032; 60760-404; 70954-076; 42708-007; 68462-141; 68180-501; 65862-098; 70518-0039; 53002-2535; 71205-924; 54458-965; 80425-0042; 53104-7574; 68071-1993; 50090-4896; 70518-0200; 43353-038; 0395-8154; 68071-1994; 68071-2184; 60687-199; 53002-1535; 80425-0083; 65862-223; 68180-189; 68788-1701; 0597-0029; 70518-2631; 0597-0030; 64380-715; 68788-9418; 50268-525; 71610-380; 68462-140; 63629-3328; 29300-124; 69097-158; 76420-043; 51655-731; 63629-2019; 58118-1158; 68788-7726; 53002-2537; 71335-1956; 63629-7966; 64380-716; 71335-1618; 65841-004; 63187-082; 62938-0026; 63187-083; 71610-516; 68180-188; 16571-777; 70518-1299; 51927-0032; 70518-0031; 49999-869; 80425-0044; 76420-039; 51655-577; 63629-3248; 55289-272; 70518-0171; 22365-116; 58624-0430
Synonyms Meloxicam | Miloxicam | Parocin | Mobic | Mobicox | Mobec | Masflex | Movicox | Reumoxicam | Uticox | Movalis
Chemical Information
Molecular Formula C14H13N3O4S2
CAS Registry Number 71125-38-7
SMILES CC1=CN=C(S1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hypertensive crisis24.08.01.0010.000147%Not Available
Hypoaesthesia17.02.06.023--Not Available
Hypokalaemia14.05.03.0020.000440%
Hyponatraemia14.05.04.0020.000220%
Hypotension24.06.03.0020.000367%
Hypothyroidism14.11.01.012; 05.02.03.0010.000110%
Hypovolaemia14.05.05.0020.000147%Not Available
Ileus07.13.01.0010.000110%
Inappropriate affect19.04.01.005--Not Available
Increased appetite08.01.09.027; 14.03.01.003--Not Available
Influenza22.07.02.001; 11.05.03.001--Not Available
Influenza like illness08.01.03.010--
Insomnia19.02.01.002; 17.15.03.002--
Interstitial lung disease22.01.02.003; 10.02.01.0330.000147%Not Available
Intestinal perforation07.04.06.0020.000073%Not Available
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.0040.000110%Not Available
Joint swelling15.01.02.0040.000147%Not Available
Kyphosis15.10.04.0020.000073%
Large intestinal ulcer07.04.06.0040.000110%
Laryngeal oedema23.04.01.005; 22.04.02.001; 10.01.05.0030.000073%
Leukopenia01.02.02.0010.000147%Not Available
Linear IgA disease23.03.01.015; 10.04.02.0060.000110%Not Available
Lip oedema10.01.05.004; 07.05.04.004; 23.04.01.0060.000110%Not Available
Lip swelling23.04.01.007; 10.01.05.005; 07.05.04.0050.000073%Not Available
Liver disorder09.01.08.0010.000073%Not Available
Local swelling08.01.03.0130.000073%Not Available
Loss of consciousness17.02.04.004--Not Available
Lung disorder22.02.07.0010.000073%Not Available
Lymphopenia01.02.02.0020.000147%Not Available
Malaise08.01.01.0030.000367%
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