Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mebendazole
Drug ID BADD_D01353
Description A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Indications and Usage For the treatment of Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections.
Marketing Status Prescription; Discontinued
ATC Code P02CA01
DrugBank ID DB00643
KEGG ID D00368
MeSH ID D008463
PubChem ID 4030
TTD Drug ID D0J1MI
NDC Product Code 49452-4395; 59285-011; 64896-669; 73309-120; 50458-675; 12578-618; 53104-7510; 69766-038; 90027-001
Synonyms Mebendazole | Vermidil | Wormkuur | Anti-Worm | Anti Worm | Bantenol | Banworm | Boots Threadworm Treatment | Lomper | Madicure | Mebendan | Mebenvet | Pripsen Mebendazole | R17635 | Sqworm | Sufil | Telmin | Vermicol | Surfont | Vermox
Chemical Information
Molecular Formula C16H13N3O3
CAS Registry Number 31431-39-7
SMILES COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CC=C3
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Neutropenia01.02.03.004--Not Available
Pain in extremity15.03.04.0100.096206%
Pruritus23.03.12.0010.036077%
Pyrexia08.05.02.0030.048103%
Rash23.03.13.0010.048103%Not Available
Seizure17.12.03.0010.036077%
Syncope24.06.02.012; 17.02.04.008; 02.01.02.0080.024051%
Syndactyly15.11.07.015; 03.11.07.0150.024051%Not Available
Talipes15.11.07.007; 03.11.07.0070.036077%Not Available
Tremor17.01.06.0020.048103%
Urticaria23.04.02.001; 10.01.06.0010.024051%
Vomiting07.01.07.0030.096206%
Pruritus generalised23.03.12.0030.024051%Not Available
Toxic skin eruption23.03.05.003; 10.01.01.0080.024051%Not Available
Skin toxicity23.03.03.032; 12.03.01.0200.024051%Not Available
Congenital hand malformation15.11.07.005; 03.11.07.0050.024051%Not Available
Liver function test increased13.03.01.044--Not Available
Somatic symptom disorder19.24.01.0060.024051%Not Available
Helminthic infection11.08.03.001; 07.19.02.0180.024051%Not Available
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