Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Magnesium sulfate
Drug ID BADD_D01343
Description A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual, 1992, p1083)
Indications and Usage Used for immediate control of life-threatening convulsions in the treatment of severe toxemias (pre-eclampsia and eclampsia) of pregnancy and in the treatment of acute nephritis in children. Also indicated for replacement therapy in magnesium deficiency, especially in acute hypomagnesemia accompanied by signs of tetany similar to those of hypocalcemia. Also used in uterine tetany as a myometriat relaxant.
Marketing Status Prescription
ATC Code A06AD04; A12CC02; B05XA05; D11AX05; V04CC02
DrugBank ID DB00653
KEGG ID D01108
MeSH ID D008278
PubChem ID 24083
TTD Drug ID D02LDN
NDC Product Code 36800-602; 0409-1754; 55301-602; 55316-602; 44567-410; 55910-648; 68196-395; 52584-642; 72288-602; 51662-1373; 37012-602; 44567-420; 11673-200; 50438-001; 71569-602; 71611-025; 63941-602; 56062-602; 44567-423; 56062-952; 55315-395; 0869-0602; 44567-424; 51662-1451; 0409-2168; 49035-602; 72476-602; 44567-422; 41250-602; 0363-0395; 51662-1372; 69256-395; 76162-029; 21130-602; 36800-395; 70000-0021; 0363-0942; 50594-602; 69842-602; 42681-6413; 67091-352; 0404-9902; 55910-038; 63940-080; 51662-1352; 30142-602; 41190-602; 68998-395; 62011-0362; 20276-330; 41163-602; 42681-6412; 0395-0807; 55570-310; 78107-001; 63940-602; 63868-602; 41250-929; 55312-029; 11673-602; 51662-1390; 30400-210; 52584-064; 53943-602; 67706-0006; 55319-395; 44567-421
Synonyms Magnesium Sulfate | Sulfate, Magnesium | Magnesium Sulfate, Heptahydrate | Heptahydrate Magnesium Sulfate
Chemical Information
Molecular Formula MgSO4
CAS Registry Number 7487-88-9
SMILES [O-]S(=O)(=O)[O-].[Mg+2]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Blood pressure decreased13.14.03.002--Not Available
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypocalcaemia14.04.01.004--
Hypothermia12.05.03.001; 08.05.01.003--
Rectal haemorrhage24.07.02.018; 07.12.03.001--
Respiratory depression22.02.01.010; 17.02.05.047--Not Available
Stupor19.02.05.004; 17.02.04.007--Not Available
Absent bowel movement07.02.02.013--Not Available
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