Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Lurasidone
Drug ID BADD_D01330
Description Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Indications and Usage Treatment of schizophrenia.
Marketing Status approved; investigational
ATC Code N05AE05
DrugBank ID DB08815
KEGG ID D04820
MeSH ID D000069056
PubChem ID 213046
TTD Drug ID D01QGX
NDC Product Code 50370-0036
UNII 22IC88528T
Synonyms Lurasidone Hydrochloride | Hydrochloride, Lurasidone | Lurasidone HCl | HCl, Lurasidone | SM 13496 | 13496, SM | SM13496 | SM-13,496 | SM 13,496 | SM13,496 | SM-13496 | Lurasidone | N-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinylmethyl)-1-cyclohexylmethyl)-2,3-bicyclo(2.2.1)heptanedicarboximide | Latuda
Chemical Information
Molecular Formula C28H36N4O2S
CAS Registry Number 367514-87-2
SMILES C1CCC(C(C1)CN2CCN(CC2)C3=NSC4=CC=CC=C43)CN5C(=O)C6C7CCC(C7)C6C5=O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Affect lability19.04.01.0010.002000%Not Available
Bipolar disorder19.16.01.0030.004525%Not Available
Major depression19.15.01.0030.000721%Not Available
Dyslipidaemia14.08.04.015--Not Available
Restless legs syndrome17.02.07.008; 15.05.03.0120.003509%Not Available
Angiopathy24.03.02.007--Not Available
Hot flush08.01.03.027; 24.03.01.005; 21.02.02.001--
Neurological symptom17.02.05.0100.000721%Not Available
Breast disorder21.05.04.004--Not Available
Cardiac disorder02.11.01.003--Not Available
Connective tissue disorder10.04.04.026; 15.06.01.006--Not Available
Electrocardiogram change13.14.05.014--Not Available
Eye movement disorder06.05.02.008; 17.02.05.0250.001443%Not Available
Feeding disorder19.09.01.003; 14.03.02.0030.000721%Not Available
Infestation23.11.01.002; 11.09.01.001--Not Available
Malnutrition14.03.02.004--Not Available
Mental disorder19.07.01.0020.003542%Not Available
Abnormal behaviour19.01.01.0010.002886%Not Available
Decreased appetite08.01.09.028; 14.03.01.005--
Erectile dysfunction21.03.01.007; 19.08.04.001--
Respiratory disorder neonatal18.04.09.002; 22.11.01.0020.000328%Not Available
Inner ear disorder04.04.02.002--Not Available
Parkinson's disease17.01.05.0100.000328%Not Available
Blood disorder01.05.01.004--Not Available
Drug intolerance08.06.01.0130.004624%Not Available
Psychotic disorder19.03.01.0020.004197%
Hepatobiliary disease09.01.08.003--Not Available
Renal impairment20.01.03.0100.001804%Not Available
Poor quality sleep17.15.04.002; 19.02.05.0050.000721%Not Available
Facial spasm17.04.03.0100.001115%Not Available
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