Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Lurasidone
Drug ID BADD_D01330
Description Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Indications and Usage Treatment of schizophrenia.
Marketing Status Prescription
ATC Code N05AE05
DrugBank ID DB08815
KEGG ID D04820
MeSH ID D000069056
PubChem ID 213046
TTD Drug ID D01QGX
NDC Product Code 50370-0036
Synonyms Lurasidone Hydrochloride | Hydrochloride, Lurasidone | Lurasidone HCl | HCl, Lurasidone | SM 13496 | 13496, SM | SM13496 | SM-13,496 | SM 13,496 | SM13,496 | SM-13496 | Lurasidone | N-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinylmethyl)-1-cyclohexylmethyl)-2,3-bicyclo(2.2.1)heptanedicarboximide | Latuda
Chemical Information
Molecular Formula C28H36N4O2S
CAS Registry Number 367514-87-2
SMILES C1CCC(C(C1)CN2CCN(CC2)C3=NSC4=CC=CC=C43)CN5C(=O)C6C7CCC(C7)C6C5=O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Malnutrition14.03.02.004--Not Available
Mental disorder19.07.01.0020.001592%Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Erectile dysfunction21.03.01.007; 19.08.04.001--
Respiratory disorder neonatal18.04.09.002; 22.11.01.0020.001592%Not Available
Inner ear disorder04.04.02.002--Not Available
Parkinson's disease17.01.05.010--Not Available
Blood disorder01.05.01.004--Not Available
Drug intolerance08.06.01.0130.003185%Not Available
Psychotic disorder19.03.01.0020.011147%
Hepatobiliary disease09.01.08.003--Not Available
Renal impairment20.01.03.010--Not Available
Facial spasm17.04.03.0100.001592%Not Available
Suicidal behaviour19.12.01.006--Not Available
Activation syndrome19.06.02.008; 17.02.05.0410.006370%Not Available
Psychiatric decompensation19.01.02.0100.003185%Not Available
Dementia with Lewy bodies19.20.02.003; 17.03.01.004--Not Available
Oromandibular dystonia17.01.03.006--Not Available
Acute kidney injury20.01.03.016--
Maternal drugs affecting foetus18.03.03.009; 12.03.03.0060.004777%Not Available
Umbilical cord around neck18.04.14.0040.002389%Not Available
Violence-related symptom19.05.01.0220.001592%Not Available
Excessive eye blinking17.17.02.010; 06.05.01.0040.001592%Not Available
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