Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Lurasidone
Drug ID BADD_D01330
Description Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Indications and Usage Treatment of schizophrenia.
Marketing Status Prescription
ATC Code N05AE05
DrugBank ID DB08815
KEGG ID D04820
MeSH ID D000069056
PubChem ID 213046
TTD Drug ID D01QGX
NDC Product Code 50370-0036
Synonyms Lurasidone Hydrochloride | Hydrochloride, Lurasidone | Lurasidone HCl | HCl, Lurasidone | SM 13496 | 13496, SM | SM13496 | SM-13,496 | SM 13,496 | SM13,496 | SM-13496 | Lurasidone | N-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinylmethyl)-1-cyclohexylmethyl)-2,3-bicyclo(2.2.1)heptanedicarboximide | Latuda
Chemical Information
Molecular Formula C28H36N4O2S
CAS Registry Number 367514-87-2
SMILES C1CCC(C(C1)CN2CCN(CC2)C3=NSC4=CC=CC=C43)CN5C(=O)C6C7CCC(C7)C6C5=O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Influenza11.05.03.001; 22.07.02.001--Not Available
Insomnia19.02.01.002; 17.15.03.0020.006370%
Intentional self-injury12.01.08.036; 19.12.01.0020.001592%Not Available
Irritability19.04.02.013; 08.01.03.0110.003981%
Jaundice neonatal18.04.08.001; 09.01.01.008; 01.06.04.0060.001592%Not Available
Joint stiffness15.01.02.003--Not Available
Ketoacidosis14.01.01.0080.001592%Not Available
Laryngospasm22.04.02.0020.001592%
Lethargy19.04.04.004; 17.02.04.003; 08.01.01.008--
Leukopenia01.02.02.0010.002389%Not Available
Libido decreased21.03.02.005; 19.08.03.0010.001592%
Lip swelling23.04.01.007; 10.01.05.005; 07.05.04.0050.003185%Not Available
Loss of consciousness17.02.04.0040.003185%Not Available
Lyme disease23.09.01.011; 15.03.03.006; 17.06.09.002; 11.02.17.0010.001592%Not Available
Malaise08.01.01.0030.009555%
Mania19.16.02.0020.007166%
Memory impairment19.20.01.003; 17.03.02.003--
Menopausal symptoms21.02.02.002--Not Available
Middle insomnia19.02.01.003; 17.15.03.0030.001592%Not Available
Migraine24.03.05.003; 17.14.02.0010.001592%Not Available
Movement disorder17.01.02.0100.001592%Not Available
Muscle rigidity17.05.02.005; 15.05.04.0010.003981%Not Available
Muscle spasms15.05.03.004--
Muscle twitching15.05.03.0050.003981%Not Available
Myalgia15.05.02.001--
Myocardial infarction24.04.04.009; 02.02.02.007--
Nasopharyngitis11.01.13.002; 22.07.03.002--Not Available
Nausea07.01.07.001--
Neck pain15.03.04.009--
Nervous system disorder17.02.10.001--Not Available
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