Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Lurasidone
Drug ID BADD_D01330
Description Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Indications and Usage Treatment of schizophrenia.
Marketing Status approved; investigational
ATC Code N05AE05
DrugBank ID DB08815
KEGG ID D04820
MeSH ID D000069056
PubChem ID 213046
TTD Drug ID D01QGX
NDC Product Code 50370-0036
UNII 22IC88528T
Synonyms Lurasidone Hydrochloride | Hydrochloride, Lurasidone | Lurasidone HCl | HCl, Lurasidone | SM 13496 | 13496, SM | SM13496 | SM-13,496 | SM 13,496 | SM13,496 | SM-13496 | Lurasidone | N-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinylmethyl)-1-cyclohexylmethyl)-2,3-bicyclo(2.2.1)heptanedicarboximide | Latuda
Chemical Information
Molecular Formula C28H36N4O2S
CAS Registry Number 367514-87-2
SMILES C1CCC(C(C1)CN2CCN(CC2)C3=NSC4=CC=CC=C43)CN5C(=O)C6C7CCC(C7)C6C5=O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Blood creatine phosphokinase increased13.04.01.001--
Blood creatinine increased13.13.01.004--
Blood glucose increased13.02.02.002--Not Available
Blood pressure increased13.14.03.005--Not Available
Blood prolactin increased13.10.03.002--Not Available
Blunted affect19.04.01.0030.000721%Not Available
Bradycardia02.03.02.002--Not Available
Bradykinesia17.01.02.004--Not Available
Breast cancer21.05.01.003; 16.10.01.001--Not Available
Breast discharge21.05.05.0010.002394%Not Available
Breast enlargement21.05.04.0010.000721%Not Available
Breast pain21.05.05.003--
Breast tenderness21.05.05.0040.000492%Not Available
Bruxism19.11.03.001; 07.01.06.0080.004066%Not Available
Cardiovascular disorder24.03.02.009; 02.11.01.010--Not Available
Catatonia19.11.01.0010.000492%Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Chills15.05.03.016; 08.01.09.0010.002722%
Choking sensation19.01.02.002; 22.12.03.0040.000492%Not Available
Chromaturia20.02.01.0020.000328%
Cogwheel rigidity17.01.05.001; 15.05.04.006--Not Available
Completed suicide19.12.01.001; 08.04.01.0100.002459%Not Available
Conversion disorder19.24.01.0010.001115%Not Available
Coordination abnormal17.02.02.004--Not Available
Crying19.04.02.002; 17.02.05.013; 12.02.11.001; 08.01.03.0050.003115%Not Available
Decreased activity19.11.01.002; 08.01.01.0060.002787%Not Available
Delusion19.10.01.0010.001935%
Depressed mood19.15.02.0010.007575%Not Available
Depression19.15.01.0010.013281%
Dermatitis23.03.04.002--Not Available
The 2th Page    First    Pre   2 3 4 5 6    Next   Last    Total 10 Pages