Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Lurasidone
Drug ID BADD_D01330
Description Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Indications and Usage Treatment of schizophrenia.
Marketing Status Prescription
ATC Code N05AE05
DrugBank ID DB08815
KEGG ID D04820
MeSH ID D000069056
PubChem ID 213046
TTD Drug ID D01QGX
NDC Product Code 50370-0036
Synonyms Lurasidone Hydrochloride | Hydrochloride, Lurasidone | Lurasidone HCl | HCl, Lurasidone | SM 13496 | 13496, SM | SM13496 | SM-13,496 | SM 13,496 | SM13,496 | SM-13496 | Lurasidone | N-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinylmethyl)-1-cyclohexylmethyl)-2,3-bicyclo(2.2.1)heptanedicarboximide | Latuda
Chemical Information
Molecular Formula C28H36N4O2S
CAS Registry Number 367514-87-2
SMILES C1CCC(C(C1)CN2CCN(CC2)C3=NSC4=CC=CC=C43)CN5C(=O)C6C7CCC(C7)C6C5=O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Blood glucose increased13.02.02.0020.005574%Not Available
Blood pressure increased13.14.03.005--Not Available
Blood prolactin increased13.10.03.0020.003185%Not Available
Bradycardia02.03.02.002--Not Available
Bradykinesia17.01.02.004--Not Available
Breast discharge21.05.05.0010.002389%Not Available
Breast enlargement21.05.04.001--Not Available
Breast pain21.05.05.003--
Bruxism19.11.03.001; 07.01.06.0080.001592%Not Available
Cardiovascular disorder24.03.02.009; 02.01.01.001--Not Available
Catatonia19.11.01.0010.001592%Not Available
Cellulitis23.09.01.001; 11.02.01.0010.001592%Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.011--Not Available
Chills15.05.03.016; 08.01.09.0010.003185%
Choking sensation19.01.02.002; 22.02.05.0020.001592%Not Available
Chromaturia20.02.01.0020.001592%
Cogwheel rigidity17.01.05.001; 15.05.04.006--Not Available
Completed suicide08.04.01.010; 19.12.01.0010.002077%Not Available
Confusional state19.13.01.001; 17.02.03.005--
Conversion disorder19.24.01.0010.001592%Not Available
Crying08.01.03.005; 19.04.02.002; 17.02.05.013; 12.02.11.0010.002389%Not Available
Death08.04.01.001--
Decreased activity19.11.01.002; 08.01.01.0060.001592%Not Available
Dehydration14.05.05.0010.003981%
Delusion19.10.01.0010.003185%
Depressed mood19.15.02.0010.004777%Not Available
Depression19.15.01.0010.011944%
Dermatitis23.03.04.002--Not Available
Dermatitis allergic10.01.03.014; 23.03.04.0030.001592%Not Available
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