Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Lomefloxacin
Drug ID BADD_D01309
Description Lomefloxacin is a fluoroquinolone antibiotic, used to treat bacterial infections including bronchitis and urinary tract infections (UTIs). Additionally, it has been employed for the prophylaxis of UTIs prior to surgery as well.
Indications and Usage For the treatment of bacterial infections of the respiratory tract (chronic bronchitis) and urinary tract, and as a pre-operative prophylactic to prevent urinary tract infection caused by: S.pneumoniae, H.influenzae, S.aureus, P.aeruginosa, E. cloacae, P. mirabilis, C. civersus, S. asprphyticus, E.coli, and K.pneumoniae.
Marketing Status Discontinued
ATC Code J01MA07; S01AE04
DrugBank ID DB00978
KEGG ID D02318
MeSH ID C053091
PubChem ID 3948
TTD Drug ID D02KOF
NDC Product Code Not Available
Synonyms lomefloxacin | lomenfloxacin | 1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid | lomefloxacin hydrochloride | Maxaquin | Logiflox | Ocacin | Okacin | Okacyn | SC 4711 | SC-4711 | Décalogiflox | NY 198 | NY-198
Chemical Information
Molecular Formula C17H19F2N3O3
CAS Registry Number 98079-51-7
SMILES CCN1C=C(C(=O)C2=CC(=C(C(=C21)F)N3CCNC(C3)C)F)C(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Ill-defined disorder08.01.03.049--Not Available
Lacrimal disorder06.08.02.005--Not Available
Pulmonary function test decreased13.19.01.001--Not Available
Respiratory tract infection22.07.07.001; 11.01.08.017--Not Available
Gastrointestinal inflammation07.08.03.007--Not Available
Vulvovaginal mycotic infection21.14.02.004; 11.03.05.004--Not Available
Candida infection11.03.03.021--
Depersonalisation/derealisation disorder19.14.01.004--Not Available
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