Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Lithium carbonate
Drug ID BADD_D01303
Description Lithium has been used to treat manic episodes since the 19th century[A176642]. Though it is widely used, its mechanism of action is still unknown[FDA Label][A14585,A176642,A176651,L5843]. Lithium carbonate has a narrow therapeutic range and so careful monitoring is required to avoid adverse effects[FDA Label].
Indications and Usage Lithium is used as a mood stabilizer, and is indicated for the treatment of manic episodes and maintenance of bipolar disorder[FDA Label].
Marketing Status approved
ATC Code Not Available
DrugBank ID DB14509
KEGG ID D00801
MeSH ID D016651
PubChem ID 11125
TTD Drug ID D04UUH
NDC Product Code 31722-546; 62332-148; 62756-430; 63187-304; 64980-205; 68462-221; 70518-0608; 70518-2312; 70518-2345; 70518-3565; 72789-171; 72789-172; 31722-544; 62332-014; 68071-2714; 0054-8531; 46708-303; 55154-4920; 63629-1916; 0378-1450; 70518-0668; 70518-3681; 0054-4527; 62332-013; 68462-220; 68462-222; 68462-223; 70518-0437; 70518-2699; 68084-655; 70518-1434; 0054-2531; 71335-0120; 0054-8528; 0615-8302; 50090-3917; 58118-0545; 0054-8526; 51079-142; 63629-1917; 68462-224; 71610-557; 72789-173; 39345-5104; 46708-305; 0378-1300; 64980-278; 70518-1753; 70518-2086; 0054-2526; 31722-545; 50090-1470; 62332-015; 62559-280; 0054-0020; 68428-481; 0054-2527; 72789-174; 82388-001; 46708-148; 50090-6052; 64117-256; 0054-0021; 68084-640; 70518-0904; 70518-1481; 0054-8527; 66039-947; 73309-248; 23155-763; 42291-496; 43063-901; 46708-304; 51079-180
UNII 2BMD2GNA4V
Synonyms Lithium Carbonate | Carbonate, Lithium | Dilithium Carbonate | Carbonate, Dilithium | Lithane | Lithium Bicarbonate | Bicarbonate, Lithium | Lithobid | Lithonate | CP-15,467-61 | CP 15,467 61 | CP15,46761 | Micalith | NSC-16895 | NSC 16895 | NSC16895 | Priadel | Quilinorm-retard | Quilinorm retard | Quilinormretard | Eskalith | Lithotabs
Chemical Information
Molecular Formula CLi2O3
CAS Registry Number 554-13-2
SMILES [Li+].[Li+].C(=O)([O-])[O-]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Tinnitus04.04.01.002; 17.04.07.004--
Tongue paralysis17.04.09.001; 07.14.02.012--Not Available
Tooth disorder07.09.05.0010.001178%Not Available
Toxic encephalopathy17.13.01.004; 12.03.01.0270.000803%Not Available
Tremor17.01.06.0020.014884%
Unresponsive to stimuli17.02.05.0310.001874%Not Available
Urinary incontinence20.02.02.010; 17.05.01.008--
Vertigo17.02.12.002; 04.04.01.003--
Vision blurred06.02.06.007; 17.17.01.010--
Visual field defect17.17.01.001; 06.02.07.003--Not Available
Visual impairment06.02.10.013--Not Available
Vomiting07.01.07.003--
Weight decreased13.15.01.005--
Weight increased13.15.01.006--
Withdrawal syndrome19.07.06.023; 08.06.02.0120.000803%Not Available
Mental status changes19.07.01.0010.005889%Not Available
Tubulointerstitial nephritis20.05.02.0020.002409%Not Available
Cardiotoxicity12.03.01.007; 02.11.01.0090.001606%Not Available
Congenital limb hyperextension15.11.07.013; 03.11.07.013--Not Available
Chapped lips07.05.01.0040.000535%Not Available
Brain death17.02.03.003; 08.04.01.0040.000535%Not Available
Left ventricular dysfunction02.04.02.0110.000803%
Balance disorder08.01.03.081; 17.02.02.0070.001338%Not Available
Dysstasia15.03.05.011; 08.01.03.089; 17.02.02.0120.000535%Not Available
Self-injurious ideation19.12.01.0070.000535%Not Available
Angiomyolipoma15.09.01.002; 16.18.01.0020.000535%Not Available
Drug tolerance decreased08.06.01.024--Not Available
Musculoskeletal discomfort15.03.04.001--Not Available
Affect lability19.04.01.0010.000535%Not Available
Bipolar disorder19.16.01.0030.001446%Not Available
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ADReCS-Target
Drug Name ADR Term Target
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