| Pharmaceutical Information |
| Drug Name |
Liothyronine sodium |
| Drug ID |
BADD_D01297 |
| Description |
Liothyronine is a thyroidal hormone T3 which is normally produced by the thyroid gland in a ratio 4:1 when compared with T4: T3. Liothyronine is the active form of thyroxine which is composed in a basic chemical structure by a tyrosine with bound iodine.[T457] The exogenous liothyronine product was developed by King Pharmaceuticals and FDA approved in 1956.[L5578] |
| Indications and Usage |
Used as replacement or supplemental therapy in patients with hypothyroidism of any etiology, except transient hypothyrodism during the recovery phase of subacute thyroiditis. |
| Marketing Status |
Prescription |
| ATC Code |
H03AA02 |
| DrugBank ID |
DB00279
|
| KEGG ID |
D01011
|
| MeSH ID |
D014284
|
| PubChem ID |
23666110
|
| TTD Drug ID |
D0S6JG
|
| NDC Product Code |
70771-1606; 60687-625; 70771-1607; 51862-320; 59762-1206; 71335-1671; 71335-1978; 60793-117; 62756-590; 67891-003; 70771-1608; 16714-167; 61919-239; 63629-8337; 38779-0031; 42291-418; 68382-582; 42291-417; 68788-7269; 42794-019; 42023-120; 0093-2180; 42794-018; 68382-584; 71335-0166; 71335-2001; 38779-3226; 50090-3131; 16714-168; 0093-2179; 62756-591; 43742-0956; 51407-384; 62991-1096; 51407-386; 39822-0151; 62756-589; 59762-1207; 0093-2178; 42794-020; 60793-115; 51407-385; 69575-4010; 60793-116; 71335-0341; 0395-8072; 42291-419; 71335-1943; 43063-884; 68382-583; 50090-5586; 51552-0354; 59762-1208; 71205-150; 63629-8154; 51862-322; 16714-166; 51862-321 |
| Synonyms |
Triiodothyronine | T3 Thyroid Hormone | Thyroid Hormone, T3 | Liothyronine | 3,3',5-Triiodothyronine | Liothyronine Sodium | Cytomel |
|
| Chemical Information |
| Molecular Formula |
C15H11I3NNaO4 |
| CAS Registry Number |
55-06-1 |
| SMILES |
C1=CC(=C(C=C1OC2=C(C=C(C=C2I)CC(C(=O)[O-])N)I)I)O.[Na+] |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
|
| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
|
ADR Severity Grade (FAERS)
|
ADR Severity Grade (CTCAE)
|
| Dermatitis allergic | 23.03.04.003; 10.01.03.014 | - | - | Not Available |
|
The 1th Page
1
Total 1 Pages
|
|
