Drug Name |
Linagliptin |
Drug ID |
BADD_D01292 |
Description |
Linagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes [L9557]. Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and obeys concentration dependant protein binding[A37050]. Linagliptin was approved by the FDA on May 2, 2011[L9557]. |
Indications and Usage |
Linagliptin is used for the management of type 2 diabetes mellitus. |
Marketing Status |
Prescription |
ATC Code |
A10BH05 |
DrugBank ID |
DB08882
|
KEGG ID |
D09566
|
MeSH ID |
D000069476
|
PubChem ID |
10096344
|
TTD Drug ID |
D02EYG
|
NDC Product Code |
69037-0008; 0597-0140; 53104-7701; 46708-892; 50090-4383; 65862-970; 55111-972; 50370-0045; 65727-057; 62993-0808; 12714-153; 62756-492; 55154-0410; 63415-0521; 66039-908; 65015-854 |
Synonyms |
Linagliptin | (R)-8-(3-amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione | 1H-purine-2,6-dione, 8-((3r)-3-amino-1-piperidinyl)-7-(2-butynyl)-3,7-dihydro-3-methyl-1-((4-methyl-2-quinazolinyl)methyl)- | BI 1356 | 1356, BI | BI1356 | BI-1356 | Tradjenta | Trajenta |