Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Levorphanol
Drug ID BADD_D01282
Description A narcotic analgesic that may be habit-forming. It is nearly as effective orally as by injection.
Indications and Usage For the management of moderate to severe pain or as a preoperative medication where an opioid analgesic is appropriate.
Marketing Status Prescription; Discontinued
ATC Code Not Available
DrugBank ID DB00854
KEGG ID D08123
MeSH ID D007981
PubChem ID 5359272
TTD Drug ID D0T3HY
NDC Product Code Not Available
Synonyms Levorphanol | Levodroman | Levorphan | Levorphanol Tartrate | Tartrate, Levorphanol | Levo-Dromoran | Levo Dromoran | LevoDromoran | 3-Hydroxy-N-methylmorphinan | 3 Hydroxy N methylmorphinan | L-Dromoran | L Dromoran
Chemical Information
Molecular Formula C17H23NO
CAS Registry Number 297-90-5
SMILES CN1CCC23CCCCC2C1CC4=C3C=C(C=C4)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002-
Abnormal dreams19.02.03.001; 17.15.02.001--Not Available
Agitation19.06.02.001; 17.02.05.012--
Amnesia19.20.01.001; 17.03.02.001--
Apnoea22.02.01.001--
Arrhythmia02.03.02.001--Not Available
Arthralgia15.01.02.001-
Biliary colic09.02.01.001--Not Available
Bradycardia02.03.02.002--Not Available
Cardiac arrest02.03.04.001--
Coma17.02.09.001--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001-
Cyanosis24.03.01.007; 22.02.02.007; 02.01.02.002--
Death08.04.01.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001-
Diplopia17.17.01.005; 06.02.06.002--Not Available
Dizziness02.01.02.004; 24.06.02.007; 17.02.05.003-
Dry mouth07.06.01.002-
Dyskinesia17.01.02.006--
Dyspepsia07.01.02.001-
Dyspnoea02.01.03.002; 22.02.01.004-
Dysuria20.02.02.002--
Erythema23.03.06.001-Not Available
Extrasystoles02.03.02.003--Not Available
Face oedema23.04.01.004; 10.01.05.002; 08.01.07.003-
Feeling abnormal08.01.09.014-Not Available
Flushing23.06.05.003; 08.01.03.025; 24.03.01.002--
Gastrointestinal pain07.01.05.005--
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