Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Levalbuterol tartrate
Drug ID BADD_D01264
Description Levosalbutamol, or levalbuterol, is a short-acting β2 adrenergic receptor agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). [Salbutamol] has been marketed as a racemic mixture, although beta2-agonist activity resides almost exclusively in the (R)-enantiomer. The enantioselective disposition of salbutamol and the possibility that (S)-salbutamol has adverse effects have led to the development of an enantiomerically pure (R)-salbutamol formulation known as levosalbutamol (levalbuterol).
Indications and Usage Levosalbutamol's bronchodilator properties give it indications in treatment of COPD (chronic obstructive pulmonary disease, also known as chronic obstructive lung disease) and asthma.
Marketing Status Prescription
ATC Code Not Available
DrugBank ID DB13139
KEGG ID D04703
MeSH ID D064412
PubChem ID 10349032
TTD Drug ID D02ZJI
NDC Product Code 50384-4188; 63187-876; 69988-0045; 0591-2927; 63402-510; 63629-8822; 15308-0719
Synonyms Levalbuterol | Xopenex | Levalbuterol Hydrochloride | Hydrochloride, Levalbuterol | Levosalbutamol Hydrochloride | Hydrochloride, Levosalbutamol
Chemical Information
Molecular Formula C30H48N2O12
CAS Registry Number 34391-04-3
SMILES CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O.CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O.C(C(C(=O)O)O)( C(=O)O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Pain08.01.08.004--
Pharyngitis11.01.13.003; 07.05.07.004; 22.07.03.004--
Rash23.03.13.001--Not Available
Rhinitis22.07.03.006; 11.01.13.004--
Supraventricular tachycardia02.03.03.012--
Tachycardia02.03.02.007--Not Available
Throat irritation07.05.03.004; 22.02.05.013--Not Available
Tremor17.01.06.002--
Urticaria23.04.02.001; 10.01.06.001--
Vertigo17.02.12.002; 04.04.01.003--
Viral infection11.05.04.001--Not Available
Vomiting07.01.07.003--
Vulvovaginal candidiasis21.14.02.003; 11.03.03.005--Not Available
Central nervous system stimulation25.04.01.001--Not Available
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