Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Levalbuterol
Drug ID BADD_D01262
Description Levosalbutamol, or levalbuterol, is a short-acting β2 adrenergic receptor agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). [Salbutamol] has been marketed as a racemic mixture, although beta2-agonist activity resides almost exclusively in the (R)-enantiomer. The enantioselective disposition of salbutamol and the possibility that (S)-salbutamol has adverse effects have led to the development of an enantiomerically pure (R)-salbutamol formulation known as levosalbutamol (levalbuterol).
Indications and Usage Indicated for the management of COPD (chronic obstructive pulmonary disease, also known as chronic obstructive lung disease) and asthma.
Marketing Status approved; investigational
ATC Code Not Available
DrugBank ID DB13139
KEGG ID D08124
MeSH ID D064412
PubChem ID 123600
TTD Drug ID D02ZJI
NDC Product Code 0378-9691; 0093-4147; 65862-943; 0378-9692; 63187-953; 0378-9690; 65862-944; 0093-4146; 65862-945; 0093-4145; 0378-6993; 65862-942; 0093-4148
UNII EDN2NBH5SS
Synonyms Levalbuterol | Xopenex | Levalbuterol Hydrochloride | Hydrochloride, Levalbuterol | Levosalbutamol Hydrochloride | Hydrochloride, Levosalbutamol
Chemical Information
Molecular Formula C13H21NO3
CAS Registry Number 34391-04-3
SMILES CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Muscle spasms15.05.03.004--
Myalgia15.05.02.001--
Mydriasis17.02.11.003; 06.05.03.0040.000424%Not Available
Nasal oedema22.04.03.012--Not Available
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Otitis media11.01.05.004; 04.05.01.001--
Pain08.01.08.004--
Paraesthesia17.02.06.005; 23.03.03.094--
Pharyngeal oedema23.04.01.016; 22.04.05.003; 10.01.05.0160.000424%Not Available
Pharyngitis22.07.03.004; 11.01.13.003; 07.05.07.004--
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Rhinitis11.01.13.004; 22.07.03.006--
Seizure17.12.03.0010.000193%
Shock24.06.02.002--Not Available
Sinusitis22.07.03.007; 11.01.13.005--
Sleep terror19.02.03.008; 17.15.02.0060.000424%Not Available
Supraventricular tachycardia02.03.03.0120.000193%
Syncope02.11.04.015; 24.06.02.012; 17.02.04.008--
Tachycardia02.03.02.0070.000481%Not Available
Tension19.06.02.005--Not Available
Throat irritation22.12.03.029; 07.05.05.0370.000655%Not Available
Throat tightness19.01.02.005; 22.12.03.0310.000193%Not Available
Tremor17.01.06.0020.000616%
Type I hypersensitivity10.01.03.006--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vertigo17.02.12.002; 04.04.01.003--
Viral infection11.05.04.001--Not Available
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