| Drug Name |
Ketamine hydrochloride |
| Drug ID |
BADD_D01229 |
| Description |
Ketamine is an NMDA receptor antagonist with a potent anesthetic effect.[A31869] It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor hallucinogenic effects and shorter psychotomimetic effects. It was FDA approved in 1970, and from there, it has been used as an anesthetic for children or patients undergoing minor surgeries but mainly for veterinary purposes.[L1332] |
| Indications and Usage |
Reports have indicated a potential use of ketamine as a therapeutic tool for the management of depression when administered in lower doses.[A31873] These reports have increased the interest for ketamine in this area and several clinical trials are launched for this indication.[L1337, A31874] |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
N01AX03 |
| DrugBank ID |
DB01221
|
| KEGG ID |
D00711
|
| MeSH ID |
D007649
|
| PubChem ID |
15851
|
| TTD Drug ID |
D0UM7O
|
| NDC Product Code |
67457-108; 42023-115; 71872-7258; 52584-038; 0143-9509; 51927-2790; 70518-2787; 72572-320; 72572-321; 55150-438; 0404-9882; 0143-9508; 0409-2051; 52584-040; 10920-597; 38779-2880; 62991-1087; 55150-440; 42023-114; 56087-5442; 0404-9880; 0404-9881; 54382-114; 51552-0697; 67457-001; 60592-401; 67457-181; 63275-9980; 52584-037; 0409-2053; 42023-113; 49452-3912; 55150-439; 61281-8000; 51927-0120; 38779-1754 |
| Synonyms |
Ketamine | 2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone | CI-581 | CI 581 | CI581 | Ketalar | Ketaset | Ketanest | Calipsol | Kalipsol | Calypsol | Ketamine Hydrochloride |
