Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Isosorbide
Drug ID BADD_D01209
Description Isosorbide was previously available in an oral formulation for the reduction of intraocular pressure. It was approved by the FDA in 1980, but has since been discontinued. Currently, isosorbide is an organic nitrate currently available in the [isosorbide mononitrate] and [isosorbide dinitrate] forms, and is used for the prevention of angina. Refer to these drug entries for more information.
Indications and Usage
Marketing Status Discontinued
ATC Code Not Available
DrugBank ID DB09401
KEGG ID D00347
MeSH ID D007547
PubChem ID 12597
TTD Drug ID Not Available
NDC Product Code Not Available
Synonyms Isosorbide | Dianhydrosorbitol
Chemical Information
Molecular Formula C6H10O4
CAS Registry Number 652-67-5
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Disturbance in sexual arousal19.08.04.003--Not Available
Urine output increased13.13.03.002--Not Available
Hot flush24.03.01.005;;
Bacterial infection11.02.01.005--Not Available
Malnutrition14.03.02.004--Not Available
Mental disorder19.07.01.002--Not Available
Decreased appetite14.03.01.005;
Erectile dysfunction21.03.01.007;
Ill-defined disorder08.01.03.049--Not Available
Red blood cell abnormality01.07.02.006--Not Available
Autonomic neuropathy17.05.01.009--Not Available
Skin mass23.07.04.014--Not Available
Candida infection11.03.03.021--
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