Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Iron sucrose
Drug ID BADD_D01199
Description Iron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) and those who do not require dialysis. Due to less side effects than iron dextran, iron sucrose is more preferred in chronic kidney disease patients.
Indications and Usage Iron sucrose is elemental iron as an injection. It replenishes body iron stores in patients with iron deficiency.
Marketing Status Prescription; Discontinued
ATC Code B03AB02
DrugBank ID DB09146
KEGG ID D04616
MeSH ID D000077605
PubChem ID 91663255
TTD Drug ID D0M4OC
NDC Product Code 50090-4541; 0517-2325; 66022-0119; 0517-2340; 55111-974; 0517-2310; 49230-530; 76055-1001; 59353-652; 49230-534
Synonyms Ferric Oxide, Saccharated | Saccharated Ferric Oxide | Ferric Saccharate | D-Glucaric acid, iron(2+) salt (1:1) | Iron Sucrose | Iron-Saccharate | Iron Saccharate | Ferri-Saccharate | Ferri Saccharate | Iron Oxide (Saccharated) | Iron(III)-Hydroxide Sucrose Complex | Venofer | Hippiron
Chemical Information
Molecular Formula C12H29Fe5Na2O23
CAS Registry Number 8047-67-4
SMILES C(C1C(C(C(C(O1)OC2(C(C(C(O2)CO)O)O)CO)O)O)O)O.O.O.O.[OH-].[O-2].[O-2].[O-2].[O-2 ].[O-2].[O-2].[O-2].[O-2].[Na+].[Na+].[Fe+3].[Fe+3].[Fe+3].[Fe+3].[Fe+3]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Catheter site infection11.01.08.022; 08.02.02.006; 12.07.02.006--Not Available
Paraesthesia oral17.02.06.008; 07.05.03.0030.003332%Not Available
Toxic skin eruption23.03.05.003; 10.01.01.0080.001666%Not Available
Graft complication12.02.09.009--Not Available
Staphylococcal infection11.02.05.0020.001666%Not Available
Hypoperfusion24.06.02.0190.001666%Not Available
Angiopathy24.03.02.007--Not Available
Hot flush21.02.02.001; 08.01.03.027; 24.03.01.0050.003332%
Eye movement disorder17.02.05.025; 06.05.02.0080.001666%Not Available
Infestation23.09.05.001; 11.09.01.001--Not Available
Limb discomfort15.03.04.0140.004165%Not Available
Malnutrition14.03.02.004--Not Available
Mediastinal disorder22.09.03.001--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Ill-defined disorder08.01.03.049--Not Available
Inner ear disorder04.04.02.002--Not Available
Sensation of foreign body08.01.09.0020.002499%Not Available
Drug intolerance08.06.01.0130.005831%Not Available
Occult blood positive13.05.02.001--Not Available
Mixed liver injury09.01.07.0150.001666%Not Available
Oropharyngeal pain22.02.05.022; 07.05.05.004--
Peripheral artery thrombosis24.01.02.0100.001666%Not Available
Apparent death08.01.03.0620.002499%Not Available
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