Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Iron sucrose
Drug ID BADD_D01199
Description Iron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) and those who do not require dialysis. Due to less side effects than iron dextran, iron sucrose is more preferred in chronic kidney disease patients.
Indications and Usage Iron sucrose is elemental iron as an injection. It replenishes body iron stores in patients with iron deficiency.
Marketing Status Prescription; Discontinued
ATC Code B03AB02
DrugBank ID DB09146
KEGG ID D04616
MeSH ID D000077605
PubChem ID 91663255
TTD Drug ID D0M4OC
NDC Product Code 50090-4541; 0517-2325; 66022-0119; 0517-2340; 55111-974; 0517-2310; 49230-530; 76055-1001; 59353-652; 49230-534
Synonyms Ferric Oxide, Saccharated | Saccharated Ferric Oxide | Ferric Saccharate | D-Glucaric acid, iron(2+) salt (1:1) | Iron Sucrose | Iron-Saccharate | Iron Saccharate | Ferri-Saccharate | Ferri Saccharate | Iron Oxide (Saccharated) | Iron(III)-Hydroxide Sucrose Complex | Venofer | Hippiron
Chemical Information
Molecular Formula C12H29Fe5Na2O23
CAS Registry Number 8047-67-4
SMILES C(C1C(C(C(C(O1)OC2(C(C(C(O2)CO)O)O)CO)O)O)O)O.O.O.O.[OH-].[O-2].[O-2].[O-2].[O-2 ].[O-2].[O-2].[O-2].[O-2].[Na+].[Na+].[Fe+3].[Fe+3].[Fe+3].[Fe+3].[Fe+3]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Dehydration14.05.05.001--
Depressed level of consciousness17.02.04.0020.001666%
Dermatitis23.03.04.002--Not Available
Dermatitis bullous23.03.01.0020.002499%
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Disorientation19.13.01.002; 17.02.05.0150.003332%Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.0040.037486%
Drug hypersensitivity10.01.01.001--Not Available
Dysgeusia17.02.07.003; 07.14.03.0010.008330%
Dyskinesia17.01.02.0060.004165%
Dyspepsia07.01.02.001--
Dysphagia07.01.06.003--
Dysphonia22.02.05.005; 19.19.03.002; 17.02.08.0040.003332%
Dyspnoea22.02.01.004; 02.01.03.0020.079137%
Ear disorder04.03.01.001--Not Available
Ear pain04.03.01.003--
Erythema23.03.06.0010.017493%Not Available
Extravasation08.01.03.0080.064143%Not Available
Eye disorder06.08.03.001--Not Available
Face oedema10.01.05.002; 08.01.07.003; 23.04.01.0040.003332%
Fatigue08.01.01.002--
Feeling abnormal08.01.09.0140.011662%Not Available
Feeling cold08.01.09.0080.010829%Not Available
Feeling hot08.01.09.0090.018326%Not Available
Fluid overload02.05.04.004; 14.05.06.001--Not Available
Flushing24.03.01.002; 23.06.05.003; 08.01.03.0250.013328%
Formication19.10.02.010; 17.02.06.0180.002499%Not Available
Gait disturbance17.02.05.016; 08.01.02.0020.004998%
Gastrointestinal disorder07.11.01.001--Not Available
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