Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ioversol
Drug ID BADD_D01186
Description Ioversol is classified as an _organoiodine_ compound and is used as a contrast dye in diagnostic procedures. It contains high levels of iodine in addition to various hydrophilic groups.
Indications and Usage Optiray 240 is indicated for cerebral angiography and venography. Optiray 240 is also indicated for contrast enhanced computed tomographic imaging of the head and body and intravenous excretory urography.
Marketing Status Prescription; Discontinued
ATC Code V08AB07
DrugBank ID DB09134
KEGG ID D01555
MeSH ID C054871
PubChem ID 3741
TTD Drug ID D0U1ZD
NDC Product Code 0019-1323; 0019-1333; 57884-0015; 0019-1332; 67684-8777; 0406-7888
Synonyms ioversol | Optiray 320 | Optiray | Optiray 300
Chemical Information
Molecular Formula C18H24I3N3O9
CAS Registry Number 87771-40-2
SMILES C(CO)N(C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I)C(=O)CO
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Rash23.03.13.001--Not Available
Rash maculo-papular23.03.13.004--
Renal colic20.02.03.010--
Renal failure20.01.03.005--Not Available
Renal infarct24.04.11.003; 20.01.07.008--Not Available
Renal tubular necrosis20.01.07.003--Not Available
Retroperitoneal haemorrhage24.07.01.017; 07.07.02.002--
Seizure17.12.03.001--
Shock24.06.02.002--Not Available
Sinus arrest02.03.03.007--Not Available
Sinus bradycardia02.03.03.009--
Sneezing22.02.05.011--
Somnolence19.02.05.003; 17.02.04.006--
Spinal cord injury17.10.04.001; 12.01.13.002--Not Available
Syncope02.01.02.008; 24.06.02.012; 17.02.04.008--
Tachycardia02.03.02.007--Not Available
Tenderness08.01.08.005--Not Available
Thrombophlebitis24.01.02.001--Not Available
Thrombosis24.01.01.006--Not Available
Tinnitus17.04.07.004; 04.04.01.002--
Tremor17.01.06.002--
Urinary retention20.02.02.011--
Urticaria23.04.02.001; 10.01.06.001--
Vascular purpura24.07.06.011; 23.06.01.008; 01.01.04.007--Not Available
Vasodilatation24.03.02.003; 23.06.05.006--Not Available
Venous thrombosis24.01.01.008--Not Available
Ventricular fibrillation02.03.04.008--
Ventricular tachycardia02.03.04.010--
Vertigo17.02.12.002; 04.04.01.003--
Vision blurred17.17.01.010; 06.02.06.007--
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