Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Iopromide
Drug ID BADD_D01182
Description Iopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration. It functions as a contrast agent by opacifying blood vessels in the path of flow of the contrast agent, permitting radiographic visualization of the internal structures until significant hemodilution occurs. Available as the FDA-approved product Ultravist, iopromide is used in radiographic studies such as intra-arterial digital subtraction angiography (IA-DSA), cerebral and peripheral arteriography, peripheral venography, excretory urography, brain computer tomography (CT), coronary arteriography, left ventriculography, visceral angiography, and aortography.
Indications and Usage Contrast computed tomography (CT) imaging of head and body (300 mg I/mL and 370 mg I/mL)
Marketing Status Prescription; Discontinued
ATC Code V08AB05
DrugBank ID DB09156
KEGG ID D01893
MeSH ID C038192
PubChem ID 3736
TTD Drug ID D07GNP
NDC Product Code 50419-346; 50419-344
Synonyms iopromide | lopromid | N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-methoxyacetamido)-N-methylisophthalamide | iopromid | Ultravist 300 | Clarograf | Ultravist
Chemical Information
Molecular Formula C18H24I3N3O8
CAS Registry Number 73334-07-3
SMILES CN(CC(CO)O)C(=O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)NC(=O)COC)I
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Bronchospasm22.03.01.004; 10.01.03.012--
Bundle branch block02.03.01.009--Not Available
Cardiac arrest02.03.04.001--
Cardiac failure02.05.01.001--
Cardiac failure congestive02.05.01.002--Not Available
Cerebral infarction24.04.06.002; 17.08.01.004--Not Available
Cerebral ischaemia24.04.06.003; 17.08.01.005--
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Chest discomfort22.02.08.001; 08.01.08.019; 02.02.02.009--Not Available
Chest pain02.02.02.011; 22.02.08.003; 08.01.08.002--Not Available
Chills08.01.09.001; 15.05.03.016--
Coma17.02.09.001--Not Available
Compartment syndrome24.04.05.006; 15.05.05.005--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Conjunctivitis11.01.06.012; 06.04.01.002--
Constipation07.02.02.001--
Coordination abnormal17.02.02.004--Not Available
Coronary artery thrombosis24.01.05.002; 02.02.01.007--Not Available
Cough22.02.03.001--
Cyanosis02.01.02.002; 24.03.01.007; 22.02.02.007--
Death08.04.01.001--
Dermatitis23.03.04.002--Not Available
Dermatitis bullous23.03.01.002--
Diabetes insipidus14.05.07.003; 05.03.03.004--Not Available
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Drug eruption23.03.05.001; 10.01.01.005; 08.01.06.015--Not Available
Dry mouth07.06.01.002--
Dysgeusia17.02.07.003; 07.14.03.001--
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