Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Iopromide
Drug ID BADD_D01182
Description Iopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration. It functions as a contrast agent by opacifying blood vessels in the path of flow of the contrast agent, permitting radiographic visualization of the internal structures until significant hemodilution occurs. Available as the FDA-approved product Ultravist, iopromide is used in radiographic studies such as intra-arterial digital subtraction angiography (IA-DSA), cerebral and peripheral arteriography, peripheral venography, excretory urography, brain computer tomography (CT), coronary arteriography, left ventriculography, visceral angiography, and aortography.
Indications and Usage Iopromide, as the product Iovist, is indicated for use as an X-ray contrast agent in the following procedures: Intra-arterial digital subtraction angiography (IA-DSA) (150 mg I/mL) Cerebral arteriography and peripheral arteriography (300 mg I/mL) Coronary arteriography and left ventriculography, visceral angiography and aortography (370 mg I/mL) Peripheral venography (240 mg I/mL) Excretory urography (300 mg I/mL) Contrast computed tomography (CT) imaging of head and body (300 mg I/mL and 370 mg I/mL)
Marketing Status approved
ATC Code V08AB05
DrugBank ID DB09156
KEGG ID D01893
MeSH ID C038192
PubChem ID 3736
TTD Drug ID D07GNP
NDC Product Code 50419-344; 50419-346; 50419-347; 50419-348
UNII 712BAC33MZ
Synonyms iopromide | lopromid | N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-methoxyacetamido)-N-methylisophthalamide | iopromid | Ultravist 300 | Clarograf | Ultravist
Chemical Information
Molecular Formula C18H24I3N3O8
CAS Registry Number 73334-07-3
SMILES CN(CC(CO)O)C(=O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)NC(=O)COC)I
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Eye oedema06.08.03.0130.035567%Not Available
Eye pruritus06.04.05.0060.109546%Not Available
Upper respiratory tract congestion22.12.03.0330.007113%Not Available
Oral pruritus07.05.05.0020.043392%Not Available
Coronary artery insufficiency02.02.01.008; 24.04.04.0160.007113%Not Available
Musculoskeletal stiffness15.03.05.0270.028454%Not Available
Musculoskeletal discomfort15.03.04.0010.007113%Not Available
Skin swelling23.03.03.0390.007113%Not Available
Injection site swelling12.07.03.018; 08.02.03.0170.010670%Not Available
Infusion site pain08.02.05.014; 12.07.05.002--Not Available
Type IV hypersensitivity reaction10.01.03.0220.010670%Not Available
Infusion site oedema12.07.05.013; 08.02.05.012--Not Available
Affect lability19.04.01.001--Not Available
Infusion site reaction12.07.05.006; 08.02.05.005--Not Available
Haemorrhage24.07.01.002--Not Available
Temperature intolerance08.01.09.0220.010670%Not Available
Rectal tenesmus15.05.03.011; 07.03.03.001--Not Available
Hypoaesthesia oral17.02.06.021; 07.05.05.0030.063309%Not Available
Paraesthesia oral07.05.05.035; 17.02.06.0080.026320%Not Available
Toxic skin eruption12.03.01.073; 23.03.05.003; 10.01.01.0080.007113%Not Available
Pulseless electrical activity02.03.04.0200.010670%Not Available
Skin oedema23.06.04.0010.007113%Not Available
Vasodilation procedure25.03.01.001--Not Available
Muscle relaxant therapy25.16.01.001--Not Available
Scleral hyperaemia06.04.07.0030.014227%Not Available
Angiopathy24.03.02.007--Not Available
Infusion site rash23.03.13.018; 12.07.05.017; 08.02.05.017--Not Available
Hot flush24.03.01.005; 21.02.02.001; 08.01.03.0270.017783%
Cardiac disorder02.11.01.003--Not Available
Connective tissue disorder10.04.04.026; 15.06.01.006--Not Available
The 13th Page    First    Pre   13 14 15    Next   Last    Total 15 Pages
ADReCS-Target
Drug Name ADR Term Target
Tip:  Drug Name  ADR Term  Protein  Variation  Gene