Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Iopromide
Drug ID BADD_D01182
Description Iopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration. It functions as a contrast agent by opacifying blood vessels in the path of flow of the contrast agent, permitting radiographic visualization of the internal structures until significant hemodilution occurs. Available as the FDA-approved product Ultravist, iopromide is used in radiographic studies such as intra-arterial digital subtraction angiography (IA-DSA), cerebral and peripheral arteriography, peripheral venography, excretory urography, brain computer tomography (CT), coronary arteriography, left ventriculography, visceral angiography, and aortography.
Indications and Usage Iopromide, as the product Iovist, is indicated for use as an X-ray contrast agent in the following procedures: Intra-arterial digital subtraction angiography (IA-DSA) (150 mg I/mL) Cerebral arteriography and peripheral arteriography (300 mg I/mL) Coronary arteriography and left ventriculography, visceral angiography and aortography (370 mg I/mL) Peripheral venography (240 mg I/mL) Excretory urography (300 mg I/mL) Contrast computed tomography (CT) imaging of head and body (300 mg I/mL and 370 mg I/mL)
Marketing Status approved
ATC Code V08AB05
DrugBank ID DB09156
KEGG ID D01893
MeSH ID C038192
PubChem ID 3736
TTD Drug ID D07GNP
NDC Product Code 50419-344; 50419-346; 50419-347; 50419-348
UNII 712BAC33MZ
Synonyms iopromide | lopromid | N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-methoxyacetamido)-N-methylisophthalamide | iopromid | Ultravist 300 | Clarograf | Ultravist
Chemical Information
Molecular Formula C18H24I3N3O8
CAS Registry Number 73334-07-3
SMILES CN(CC(CO)O)C(=O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)NC(=O)COC)I
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Rhinitis22.07.03.006; 11.01.13.004--
Rhinorrhoea22.12.03.0210.059752%
Salivary gland enlargement07.06.03.002--Not Available
Salivary hypersecretion07.06.01.0090.021340%Not Available
Seizure17.12.03.0010.131598%
Sense of oppression08.01.09.0200.007113%Not Available
Sensory loss17.02.07.0070.007113%Not Available
Sepsis11.01.11.003--
Shock24.06.02.0020.042680%Not Available
Sinus tachycardia02.03.03.0100.010670%
Skin discolouration23.03.03.0050.014227%Not Available
Skin discomfort23.03.03.0060.007113%Not Available
Skin disorder23.03.03.0070.028454%Not Available
Skin lesion23.03.03.0100.014227%Not Available
Skin necrosis23.03.03.0110.010670%Not Available
Skin reaction23.03.03.013; 10.01.03.0190.024897%Not Available
Sneezing22.12.03.0240.400484%
Soft tissue injury15.03.02.010; 12.01.08.026--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Speech disorder22.12.03.027; 19.19.02.002; 17.02.08.0030.039124%Not Available
Spleen disorder01.09.02.0030.007113%Not Available
Sputum discoloured22.02.03.0100.007113%Not Available
Stevens-Johnson syndrome10.01.01.045; 23.03.01.007; 12.03.01.014; 11.07.01.005--
Stupor19.02.05.004; 17.02.04.0070.007113%Not Available
Subarachnoid haemorrhage12.01.10.011; 24.07.04.004; 17.08.01.0100.007113%Not Available
Subcutaneous emphysema23.07.04.006; 12.02.06.0020.007113%
Suffocation feeling22.12.02.0140.046237%Not Available
Swelling08.01.03.0150.066866%Not Available
Swelling face23.04.01.018; 10.01.05.018; 08.01.03.1000.097453%Not Available
Swollen tongue23.04.01.014; 10.01.05.015; 07.14.02.0030.056196%Not Available
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ADReCS-Target
Drug Name ADR Term Target
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