Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Iohexol
Drug ID BADD_D01180
Description Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Indications and Usage Iohexol ia used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures.
Marketing Status Prescription; Discontinued
ATC Code V08AB02
DrugBank ID DB01362
KEGG ID D01817
MeSH ID D007472
PubChem ID 3730
TTD Drug ID D02BLO
NDC Product Code 0407-1411; 71806-141; 0407-1413; 0407-1412; 0407-1401; 0407-1415; 0407-1414; 0407-1416; 65072-0801
Synonyms Iohexol | Iohexol 350 | Nycodenz | Compound 545 | Exypaque | Omnipaque
Chemical Information
Molecular Formula C19H26I3N3O9
CAS Registry Number 66108-95-0
SMILES CC(=O)N(CC(CO)O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hemiplegia17.01.04.002--Not Available
Hostility19.05.01.003--Not Available
Hyperaesthesia17.02.06.004--Not Available
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hyperreflexia17.02.01.002--Not Available
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hyperthyroidism14.11.01.011; 05.02.02.001--
Hypertonia17.05.02.001; 15.05.04.007--Not Available
Hypotension24.06.03.002--
Hypotonia17.05.02.002; 15.05.04.008--Not Available
Immune system disorder10.02.01.001--Not Available
Injection site pain12.07.03.011; 08.02.03.010--Not Available
Injection site reaction12.07.03.015; 08.02.03.014--
Insomnia19.02.01.002; 17.15.03.002--
Laryngeal oedema23.04.01.005; 22.04.02.001; 10.01.05.003--
Laryngospasm22.04.02.002--
Loss of consciousness17.02.04.004--Not Available
Malaise08.01.01.003--
Meningism17.02.05.007--
Meningitis aseptic17.06.03.002; 11.01.03.002--Not Available
Meningitis bacterial17.06.10.002; 11.02.01.013--Not Available
Meningitis chemical12.03.02.004; 17.06.03.003--Not Available
Muscle contractions involuntary17.05.03.001; 15.05.03.008--Not Available
Muscle spasms15.05.03.004--
Muscle spasticity17.05.03.007; 15.05.04.011--
Muscular weakness17.05.03.005; 15.05.06.001--
Myalgia15.05.02.001--
Myelitis17.06.02.001; 11.01.03.007--
Myocardial ischaemia02.02.02.008; 24.04.04.010--Not Available
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