ADReCS

Pharmaceutical Information

Drug Name	Iohexol
Drug ID	BADD_D01180
Description	Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Indications and Usage	Iohexol ia used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures.
Marketing Status	approved
ATC Code	V08AB02
DrugBank ID	DB01362
KEGG ID	D01817
MeSH ID	D007472
PubChem ID	3730
TTD Drug ID	D02BLO
NDC Product Code	43228-100; 0407-1413; 71806-141; 0407-1414; 0407-1416; 0407-1415; 0407-1401; 0407-1411; 0407-1412; 65072-0801; 54702-501
UNII	4419T9MX03
Synonyms	Iohexol \| Iohexol 350 \| Nycodenz \| Compound 545 \| Exypaque \| Omnipaque

Chemical Information

Molecular Formula	C19H26I3N3O9
CAS Registry Number	66108-95-0
SMILES	CC(=O)N(CC(CO)O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I
Chemical Structure

ADRs Induced by Drug

*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..

ADR Term	ADReCS ID	ADR Frequency (FAERS)	ADR Severity Grade (FAERS)	ADR Severity Grade (CTCAE)
Asthenia	08.01.01.001	-	-	Not Available
Auditory disorder	04.02.03.002	-	-	Not Available
Back pain	15.03.04.005	-	-
Blindness cortical	06.02.10.004; 17.17.01.017	0.021340%		Not Available
Blindness transient	06.02.10.006; 17.17.01.004	0.024897%		Not Available
Blister	23.03.01.001; 12.01.06.002	0.129464%		Not Available
Blood pressure fluctuation	24.06.01.002	0.010670%		Not Available
Body temperature increased	13.15.01.001	-	-	Not Available
Bone disorder	15.02.04.004	-	-	Not Available
Bradycardia	02.03.02.002	0.076113%		Not Available
Bronchospasm	22.03.01.004; 10.01.03.012	0.115237%
Burning sensation	17.02.06.001; 08.01.09.029	0.079670%		Not Available
Cardiac arrest	02.03.04.001	0.117371%
Cardio-respiratory arrest	22.02.06.007; 02.03.04.002	0.153649%		Not Available
Cardiogenic shock	24.06.02.006; 02.05.01.003	0.017783%		Not Available
Cardiovascular disorder	02.11.01.010; 24.03.02.009	-	-	Not Available
Cauda equina syndrome	17.10.03.006	-	-	Not Available
Cerebral haemorrhage	17.08.01.003; 24.07.04.001	-	-	Not Available
Chest discomfort	22.12.02.002; 08.01.08.019; 02.02.02.009	0.547731%		Not Available
Chest pain	02.02.02.011; 22.12.02.003; 08.01.08.002	0.243278%		Not Available
Chills	15.05.03.016; 08.01.09.001	0.611751%
Choking	22.12.03.003	0.021340%		Not Available
Choking sensation	22.12.03.004; 19.01.02.002	0.021340%		Not Available
Circulatory collapse	24.06.02.001	0.046237%		Not Available
Cold sweat	23.02.03.002; 08.01.03.024	0.064020%		Not Available
Coma	17.02.09.001	-	-	Not Available
Compartment syndrome	24.04.05.006; 15.05.05.005	0.014227%		Not Available
Confusional state	19.13.01.001; 17.02.03.005	-	-
Conjunctival oedema	06.04.01.001	0.010670%		Not Available
Contrast media reaction	12.02.05.029; 10.01.01.011	0.817328%		Not Available

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