ADReCS

Pharmaceutical Information

Drug Name	Iodixanol
Drug ID	BADD_D01178
Description	Iodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography, particularly in individuals with renal dysfunction, as it is believed to be less toxic to the kidneys than most other intravascular contrast agents.
Indications and Usage	Iodixanol is a contrast agent during coronary angiography.
Marketing Status	approved
ATC Code	V08AB09
DrugBank ID	DB01249
KEGG ID	D01474
MeSH ID	C044834
PubChem ID	3724
TTD Drug ID	D0Y4YG
NDC Product Code	71806-222; 65219-381; 0407-2223; 65219-383; 0407-2222; 57884-0029
UNII	HW8W27HTXX
Synonyms	iodixanol \| Visipaque \| Visipaque Unique Softpac \| iodixanol-320 \| contrast media 2-5410-3

Chemical Information

Molecular Formula	C35H44I6N6O15
CAS Registry Number	92339-11-2
SMILES	CC(=O)N(CC(CN(C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I)C(=O)C)O)C2=C(C(= C(C(=C2I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I
Chemical Structure

ADRs Induced by Drug

*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..

ADR Term	ADReCS ID	ADR Frequency (FAERS)	ADR Severity Grade (FAERS)	ADR Severity Grade (CTCAE)
Blood creatinine increased	13.13.01.004	-	-
Blood pressure fluctuation	24.06.01.002	0.007113%		Not Available
Blood urea increased	13.13.01.006	-	-	Not Available
Body temperature increased	13.15.01.001	-	-	Not Available
Bone disorder	15.02.04.004	-	-	Not Available
Bradycardia	02.03.02.002	0.024897%		Not Available
Bronchitis	22.07.01.001; 11.01.09.001	-	-
Bronchospasm	22.03.01.004; 10.01.03.012	0.046237%
Bundle branch block	02.03.01.009	-	-	Not Available
Burning sensation	17.02.06.001; 08.01.09.029	0.017783%		Not Available
Cardiac arrest	02.03.04.001	0.053350%
Cardiac failure	02.05.01.001	-	-
Cardio-respiratory arrest	22.02.06.007; 02.03.04.002	0.065443%		Not Available
Cardiogenic shock	02.05.01.003; 24.06.02.006	0.017783%		Not Available
Cerebral infarction	24.04.06.002; 17.08.01.004	0.017783%		Not Available
Cerebrovascular disorder	24.03.05.002; 17.08.02.002	-	-	Not Available
Cheilitis	23.03.03.025; 07.05.01.001	0.015649%
Chest discomfort	22.12.02.002; 08.01.08.019; 02.02.02.009	0.149381%		Not Available
Chest pain	22.12.02.003; 08.01.08.002; 02.02.02.011	0.056196%		Not Available
Chills	15.05.03.016; 08.01.09.001	0.133020%
Choking	22.12.03.003	-	-	Not Available
Choking sensation	22.12.03.004; 19.01.02.002	0.007113%		Not Available
Circulatory collapse	24.06.02.001	0.017783%		Not Available
Coagulopathy	01.01.02.001	-	-	Not Available
Cold sweat	23.02.03.002; 08.01.03.024	0.042680%		Not Available
Colour blindness acquired	06.02.09.002	-	-	Not Available
Coma	17.02.09.001	-	-	Not Available
Compartment syndrome	24.04.05.006; 15.05.05.005	0.010670%		Not Available
Conduction disorder	02.03.01.008	-	-
Confusional state	19.13.01.001; 17.02.03.005	-	-

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