Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Interferon alfa-2b
Drug ID BADD_D01167
Description Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent.
Indications and Usage For the treatment of hairy cell leukemia, malignant melanoma, and AIDS-related Kaposi's sarcoma.
Marketing Status Prescription
ATC Code L03AB05
DrugBank ID DB00105
KEGG ID D02745
MeSH ID D000077190
PubChem ID 71306834
TTD Drug ID D0P0WV
NDC Product Code 0085-4350; 0085-4352; 53713-0080; 0085-1133; 53713-0082; 53713-0079; 0085-4351; 53713-0078; 0085-1168; 53713-0081
Synonyms Interferon alpha-2 | Interferon alpha 2 | Interferon-alpha 2 | Interferon alpha-A | Interferon alpha A | LeIF A | IFN-alpha 2 | IFN-alpha-2 | Interferon alfa-2a | Interferon alfa 2a | Recombinant Interferon alpha-2a | Interferon alpha-2a, Recombinant | Recombinant Interferon alpha 2a | Roferon-A | Roferon A | RoferonA | Ro 22-8181 | Ro 22 8181 | Ro 228181 | Viferon | Sch-30500 | Sch 30500 | Sch30500 | Intron A (Interferon) | Reaferon | Interferon alfa-2b | Interferon alfa 2b | Interferon alpha-2b, Recombinant | Interferon alpha 2b, Recombinant | Recombinant Interferon alpha-2b | Recombinant Interferon alpha 2b | IFNalpha-2b, Recombinant | IFNalpha 2b, Recombinant | Recombinant IFNalpha-2b
Chemical Information
Molecular Formula C16H17Cl3I2N3NaO5S
CAS Registry Number 98530-12-2
SMILES CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)N2C=CN=C2.C(S(=O)(=O)[O-])(I)I.[Na+]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Aplasia pure red cell10.02.01.003; 01.03.03.001--Not Available
Aplastic anaemia01.03.03.002--Not Available
Arrhythmia02.03.02.001--Not Available
Arrhythmia supraventricular02.03.03.001--Not Available
Arteritis24.05.01.001--Not Available
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Arthropathy15.01.01.003--Not Available
Ascites02.05.04.002; 09.01.05.003; 07.07.01.001--
Aspartate aminotransferase increased13.03.01.006--
Asthenia08.01.01.001--Not Available
Asthma22.03.01.002; 10.01.03.010--Not Available
Ataxia17.02.02.001; 08.01.02.004--
Atrial fibrillation02.03.03.002--
Auditory disorder04.02.03.002--Not Available
Back pain15.03.04.005--
Biliary colic09.02.01.001--Not Available
Bipolar I disorder19.16.01.002--Not Available
Bladder pain20.02.02.001--Not Available
Blindness17.17.01.003; 06.02.02.001--Not Available
Blood lactate dehydrogenase increased13.04.02.002--
Blood triglycerides increased13.12.03.001--Not Available
Blood urea increased13.13.01.006--Not Available
Blood uric acid increased13.02.04.001--Not Available
Body temperature decreased13.15.01.010--Not Available
Body temperature increased13.15.01.001--Not Available
Bone disorder15.02.04.004--Not Available
Bone pain15.02.01.001--
Bradycardia02.03.02.002--Not Available
Breast pain21.05.05.003--
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