| Pharmaceutical Information |
| Drug Name |
Indium in-111 pentetate disodium |
| Drug ID |
BADD_D01153 |
| Description |
Pentetic acid, also known as diethylenetriaminepentaacetic acid (DTPA), is a synthetic polyamino carboxylic acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable DTPA-metal ion complexes. DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment of internal contamination by transuranics.[A32501] It is currently considered, in all the dosage forms, as a member of the list of approved inactive ingredients for drug products by the FDA.[L2242] DPTA was developed by the pharmaceutical company CIS US and FDA approved on April 14, 2004.[L1469] |
| Indications and Usage |
Pentetate Indium Disodium In 111 is recommended for use in radionuclide cisternography. |
| Marketing Status |
Prescription |
| ATC Code |
Not Available |
| DrugBank ID |
DB14007
|
| KEGG ID |
Not Available
|
| MeSH ID |
D004369
|
| PubChem ID |
23724985
|
| TTD Drug ID |
D09NFN
|
| NDC Product Code |
17156-251 |
| Synonyms |
Pentetic Acid | Penthanil | DTPA | Pentaind | DETAPAC | Diethylenetriamine Pentaacetic Acid | Pentaacetic Acid, Diethylenetriamine | Mn-Dtpa | Zinc-DTPA | Zinc DTPA | Ca-DTPA | CaDTPA | Pentetate Calcium Trisodium | CaNa-DTPA | Calcium Trisodium Pentetate | Pentetate, Calcium Trisodium | Pentetate Zinc Trisodium | Pentetates | Sn-DTPA | Indium-DTPA | Indium DTPA | Pentacine | Pentacin |
|
| Chemical Information |
| Molecular Formula |
C14H18InN3Na2O10 |
| CAS Registry Number |
60662-14-8 |
| SMILES |
C(CN(CC(=O)[O-])CC(=O)[O-])N(CCN(CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].[Na+].[Na+].[I
n+3] |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
|
| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
|
ADR Severity Grade (FAERS)
|
ADR Severity Grade (CTCAE)
|
| Meningitis aseptic | 11.01.03.002; 17.06.03.002 | - | - | Not Available | | Pyrexia | 08.05.02.003 | - | - | | | Skin reaction | 23.03.03.013; 10.01.03.019 | - | - | Not Available | | Vomiting | 07.01.07.003 | - | - | |
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