Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Imiquimod
Drug ID BADD_D01142
Description Imiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist. Imiquimod is commonly used topically to treat warts on the skin of the genital and anal areas. Imiquimod does not cure warts, and new warts may appear during treatment. Imiquimod does not fight the viruses that cause warts directly, however, it does help to relieve and control wart production. Miquimod is also used to treat a skin condition of the face and scalp called actinic keratoses and certain types of skin cancer called superficial basal cell carcinoma.
Indications and Usage For the topical treatment of clinically typical, nonhyperkeratotic, nonhypertrophic actinic keratoses on the face or scalp in immunocompetent adults. Also indicated for the treatment of external genital and perianal warts/condyloma acuminata in individuals 12 years old and above.
Marketing Status approved; investigational
ATC Code D06BB10
DrugBank ID DB00724
KEGG ID D02500
MeSH ID D000077271
PubChem ID 57469
TTD Drug ID D06CTE
NDC Product Code 62350-0077; 68682-272; 72189-084; 0168-0432; 22365-121; 51672-4174; 99207-271; 66039-829; 71052-160; 64552-4008; 45802-368; 51552-1538; 62147-0087; 51672-4145; 63629-8818; 68462-536; 51927-0168; 72643-006; 0093-3133; 99207-260; 99207-270; 99207-276; 58175-0397; 62147-0072
UNII P1QW714R7M
Synonyms Imiquimod | 1-Isobutyl-1H-imidazo(4,5-c)quinolin-4-amine | S 26308 | S-26308 | R 837 | R-837 | R837 | Zyclara | Aldara
Chemical Information
Molecular Formula C14H16N4
CAS Registry Number 99011-02-6
SMILES CC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Lip blister07.05.01.007; 23.03.01.0160.000658%Not Available
General physical health deterioration08.01.03.0180.001317%Not Available
Balance disorder08.01.03.081; 17.02.02.0070.000439%Not Available
Application site hyperaesthesia12.07.01.023; 08.02.01.023; 17.02.06.011--Not Available
Application site paraesthesia17.02.06.012; 12.07.01.026; 08.02.01.026--Not Available
Dysstasia17.02.02.012; 15.03.05.011; 08.01.03.089--Not Available
Lupus-like syndrome15.06.02.004; 23.03.02.004; 10.04.03.0030.001536%Not Available
Acute coronary syndrome02.02.02.015; 24.04.04.011--Not Available
Conjunctival hyperaemia06.04.01.0040.000878%Not Available
Skin induration23.03.03.0200.001493%
Eye pruritus06.04.05.0060.001097%Not Available
Application site discharge23.03.03.049; 12.07.01.039; 08.02.01.039--Not Available
Respiratory tract congestion22.02.07.003--Not Available
Lymphatic disorder01.09.01.003--Not Available
Musculoskeletal stiffness15.03.05.0270.001185%Not Available
Protein urine present13.13.02.006--Not Available
Musculoskeletal discomfort15.03.04.001--Not Available
Application site swelling12.07.01.027; 08.02.01.0270.001185%Not Available
Skin burning sensation23.03.03.021; 17.02.06.009--Not Available
Scrotal erythema23.03.06.013; 21.12.02.008--Not Available
Eczema weeping23.03.04.022--Not Available
Haemorrhage24.07.01.0020.001317%Not Available
Pre-existing disease08.01.03.059--Not Available
Cutaneous lupus erythematosus23.03.02.008; 15.06.02.007; 10.04.03.0070.001097%Not Available
Rectal tenesmus15.05.03.011; 07.03.03.001--Not Available
Cognitive disorder19.21.02.001; 17.03.03.0030.001097%
Skin oedema23.06.04.001--Not Available
Application site discolouration23.03.03.023; 12.07.01.030; 08.02.01.0300.001185%Not Available
Application site scar23.03.11.010; 12.07.01.033; 08.02.01.0330.000878%Not Available
Congenital eye disorder06.08.03.011; 03.01.01.002--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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