Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Iloprost
Drug ID BADD_D01135
Description Iloprost is a synthetic analogue of prostacyclin PGI2 that dilates systemic and pulmonary arterial vascular beds. It is used to treat pulmonary arterial hypertension (PAH).
Indications and Usage Used for the treatment of pulmonary arterial hypertension.
Marketing Status Prescription; Discontinued
ATC Code B01AC11
DrugBank ID DB01088
KEGG ID D02721
MeSH ID D016285
PubChem ID 5311181
TTD Drug ID D05ZTH
NDC Product Code 54893-0017; 66215-302; 82231-109; 66215-303; 40016-013
Synonyms Iloprost | Ciloprost | ZK-36374 | ZK 36374 | ZK36374 | Ventavis
Chemical Information
Molecular Formula C22H32O4
CAS Registry Number 78919-13-8
SMILES CC#CCC(C)C(C=CC1C(CC2C1CC(=CCCCC(=O)O)C2)O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Swelling08.01.03.0150.001669%Not Available
Swelling face23.04.01.018; 10.01.05.0180.000742%Not Available
Syncope24.06.02.012; 17.02.04.008; 02.01.02.0080.004452%
Systemic lupus erythematosus23.03.02.006; 15.06.02.003; 10.04.03.0040.000371%Not Available
Tachycardia02.03.02.007--Not Available
Throat irritation22.02.05.013; 07.05.03.0040.001669%Not Available
Thrombocytopenia01.08.01.002--Not Available
Thrombosis24.01.01.006--Not Available
Tinnitus17.04.07.004; 04.04.01.002--
Transient ischaemic attack17.08.04.001; 24.04.06.005--
Trismus17.01.03.004; 15.05.04.004--
Upper respiratory tract infection22.07.03.011; 11.01.13.0090.000742%
Urinary tract infection20.08.02.001; 11.01.14.004--
Vaginal haemorrhage21.08.01.001; 24.07.03.005--
Vasodilatation24.03.02.003; 23.06.05.006--Not Available
Ventricular septal defect03.07.02.001; 02.04.02.0070.000145%Not Available
Vertigo17.02.12.002; 04.04.01.003--
Viral infection11.05.04.0010.000556%Not Available
Visual acuity reduced17.17.01.011; 06.02.03.0010.000556%
Visual impairment06.02.06.008--Not Available
Vomiting07.01.07.003--
Weight decreased13.15.01.005--
Weight increased13.15.01.006--
Wheezing22.03.01.009--
White blood cell count decreased13.01.06.012--
Yellow skin23.03.03.042; 09.01.01.009; 08.01.03.0460.000371%Not Available
Hypoacusis04.02.01.0060.000371%
Peripheral swelling08.01.03.053; 02.05.04.015--Not Available
Balance disorder17.02.02.007--Not Available
Contusion24.07.06.001; 23.03.11.002; 15.03.01.008; 12.01.06.001--
The 9th Page    First    Pre   9 10 11    Next   Last    Total 11 Pages