Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Iloprost
Drug ID BADD_D01135
Description Iloprost is a synthetic analogue of prostacyclin PGI2 that dilates systemic and pulmonary arterial vascular beds. It is used to treat pulmonary arterial hypertension (PAH).
Indications and Usage Used for the treatment of pulmonary arterial hypertension.
Marketing Status approved; investigational
ATC Code B01AC11
DrugBank ID DB01088
KEGG ID D02721
MeSH ID D016285
PubChem ID 5311181
TTD Drug ID D05ZTH
NDC Product Code 66215-303; 40016-013; 82231-109; 54893-0017; 66215-302
UNII JED5K35YGL
Synonyms Iloprost | Ciloprost | ZK-36374 | ZK 36374 | ZK36374 | Ventavis
Chemical Information
Molecular Formula C22H32O4
CAS Registry Number 78919-13-8
SMILES CC#CCC(C)C(C=CC1C(CC2C1CC(=CCCCC(=O)O)C2)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Condition aggravated08.01.03.0040.001480%Not Available
Cor pulmonale24.08.03.001; 02.05.03.001; 22.06.01.0030.000206%Not Available
Coronary artery disease02.02.01.001; 24.04.04.0060.000164%Not Available
Cough22.02.03.0010.002352%
Cyanosis23.06.04.005; 02.11.04.004; 24.03.01.007; 22.02.02.0070.000288%
Deafness04.02.01.0010.000082%Not Available
Death08.04.01.0010.040135%
Decubitus ulcer23.03.11.0060.000082%Not Available
Depressed mood19.15.02.0010.000288%Not Available
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Discomfort08.01.08.0030.000288%Not Available
Dizziness17.02.05.003; 02.11.04.006; 24.06.02.007--
Dizziness postural02.11.04.008; 24.06.02.008; 17.02.05.0040.000181%Not Available
Drug interaction08.06.03.001--Not Available
Dry throat22.12.03.005; 07.06.01.0050.000222%Not Available
Dysgeusia17.02.07.003; 07.14.03.001--
Dysphonia22.12.03.006; 17.02.08.004; 19.19.03.0020.000206%
Dyspnoea02.11.05.003; 22.02.01.0040.007057%
Dyspnoea exertional02.11.05.005; 22.02.01.0050.000387%Not Available
Electrolyte imbalance14.05.01.0020.000082%Not Available
Emphysema22.01.02.0020.000082%Not Available
Epistaxis24.07.01.005; 22.04.03.0010.000699%
Eye disorder06.08.03.0010.000082%Not Available
Eye haemorrhage24.07.05.002; 06.07.02.001; 12.02.02.0120.000082%Not Available
Eye pain06.08.03.0020.000123%
Eye swelling06.08.03.0030.000123%Not Available
Facial pain08.01.08.0120.000123%
Faeces discoloured07.01.03.0020.000082%Not Available
Feeling abnormal08.01.09.0140.000716%Not Available
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