Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Idoxuridine
Drug ID BADD_D01131
Description An analog of deoxyuridine that inhibits viral DNA synthesis. The drug is used as an antiviral agent.
Indications and Usage For use in keratoconjunctivitis and keratitis caused by herpes simplex virus.
Marketing Status Discontinued
ATC Code D06BB01; J05AB02; S01AD01
DrugBank ID DB00249
KEGG ID D00342
MeSH ID D007065
PubChem ID 5905
TTD Drug ID D09PZO
NDC Product Code Not Available
Synonyms Idoxuridine | 5-Iodo-2'-deoxyuridine | 5 Iodo 2' deoxyuridine | IUdR | 5-Iododeoxyuridine | 5 Iododeoxyuridine | Iododeoxyuridine | Herplex Liquifilm | Liquifilm, Herplex | Idoxuridine, 123I-Labeled | 123I-Labeled Idoxuridine | Idoxuridine, 123I Labeled | Idoxuridine, 125I-Labeled | 125I-Labeled Idoxuridine | Idoxuridine, 125I Labeled | Idoxuridine, 131I-Labeled | 131I-Labeled Idoxuridine | Idoxuridine, 131I Labeled | Idoxuridine, 3H-Labeled | 3H-Labeled Idoxuridine | Idoxuridine, 3H Labeled | Stoxil | Idoxuridine, Radical Ion (1-) | Kerecide | NSC-39661 | NSC 39661 | NSC39661 | Oftan-IDU | Oftan IDU | OftanIDU | SK&F-14287 | Allergan 211 | Idoxuridine, Radical Ion (+1)
Chemical Information
Molecular Formula C9H11IN2O5
CAS Registry Number 54-42-2
SMILES C1C(C(OC1N2C=C(C(=O)NC2=O)I)CO)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Blepharitis23.03.04.012; 06.04.04.001--Not Available
Burning sensation17.02.06.001; 08.01.09.029--Not Available
Conjunctivitis11.01.06.012; 06.04.01.002--
Eye irritation06.04.05.003--Not Available
Swelling08.01.03.015--Not Available
Vision blurred17.17.01.010; 06.02.06.007--
Vital dye staining cornea present13.07.04.010--Not Available
Conjunctival hyperaemia06.04.01.004--Not Available
Peripheral revascularisation25.03.01.002--Not Available
Corneal disorder06.08.01.004--Not Available
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