| Pharmaceutical Information |
| Drug Name |
Homatropine |
| Drug ID |
BADD_D01075 |
| Description |
Homatropine is an anticholinergic drug that acts as an antagonist at muscarinic acetylcholine receptors. It is present in antitussives, under the trade name Hycodan, in combination with hydrocodone (dihydrocodeinone) bitartrate indicated for the symptomatic relief of cough as oral tablets or solutions. Homatropine is included in subtherapeutic amounts as homatropine methylbromide to discourage deliberate overdosage. Homatropine hydrobromide has been administered as ophthalmic solutions as a cycloplegic to temporarily paralyze accomodation, and to induce mydriasis (the dilation of the pupil); however such therapeutic use has not been approved by the FDA to be safe and effective. |
| Indications and Usage |
|
| Marketing Status |
Not Available |
| ATC Code |
S01FA05 |
| DrugBank ID |
DB11181
|
| KEGG ID |
C07814
|
| MeSH ID |
C100236
|
| PubChem ID |
688024
|
| TTD Drug ID |
Not Available
|
| NDC Product Code |
Not Available |
| Synonyms |
homatropine | homatropine, (3(S)-endo)-isomer | homatropine, exo-(+-)-isomer | I - Homatrine | Isopto Homatropine | Minims-Homatropin | AK-Homatropine | Homatropin - POS | homatropine hydrobromide, (endo-(+-)-isomer) | homatropine hydrochloride, (endo-(+-)-isomer) | homatropine sulfate (1:1), (3(R)-endo)-isomer | homatropine sulfate (1:1), (3(S)-endo)-isomer | homatropine sulfate (2:1), endo-isomer | Minims-Homatropine Hydrobromide |
|
| Chemical Information |
| Molecular Formula |
C16H21NO3 |
| CAS Registry Number |
87-00-3 |
| SMILES |
CN1C2CCC1CC(C2)OC(=O)C(C3=CC=CC=C3)O |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
|
|
