Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Halobetasol propionate
Drug ID BADD_D01052
Description Ulobetasol is a highly potent corticosteroid.[A215597] It is structurally related to [clobetasol].[A215597] Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis and corticosteroid responsive dermatoses.[L15047,L15052,L15102] Ulobetasol was granted FDA approval on 17 December 1990.[L15047]
Indications and Usage For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Marketing Status Prescription; Discontinued
ATC Code D07AC21
DrugBank ID DB00596
KEGG ID D04409
MeSH ID C064466
PubChem ID 48175
TTD Drug ID D00XPC
NDC Product Code 0713-0758; 64918-1206; 51862-606; 52128-138; 45802-129; 63629-8735; 0713-0339; 70752-119; 51672-1321; 51862-604; 10631-122; 45802-131; 58175-0391; 0713-0640; 0187-0002; 52565-073; 63629-8665; 22552-0001; 63739-998; 0168-0355; 50909-5157; 46204-0188; 63629-8664; 51672-1322
Synonyms halobetasol | ulobetasol | Ultravate | halobetasol propionate | 6 alpha-fluoroclobetasol 17-propionate | 6-fluoroclobetasol 17-propionate | CGP 14 458 | CGP-14458 | CGP 14458
Chemical Information
Molecular Formula C25H31ClF2O5
CAS Registry Number 66852-54-8
SMILES CCC(=O)OC1(C(CC2C1(CC(C3(C2CC(C4=CC(=O)C=CC43C)F)F)O)C)C)C(=O)CCl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Acne23.02.01.001--Not Available
Burning sensation17.02.06.001; 08.01.09.029--Not Available
Dermatitis23.03.04.002--Not Available
Dermatitis acneiform23.02.01.004--
Dermatitis contact12.03.01.040; 10.01.01.003; 23.03.04.004--Not Available
Dry skin23.03.03.001--
Erythema23.03.06.001--Not Available
Folliculitis23.09.04.007; 11.01.12.018--
Hypertrichosis23.02.04.002--
Infection11.01.08.002--Not Available
Leukoderma23.05.02.001--Not Available
Miliaria23.02.03.014--Not Available
Pain08.01.08.004--
Paraesthesia17.02.06.005--
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Rash pustular23.03.10.003; 11.01.12.002--
Skin atrophy23.01.05.001--
Skin hypopigmentation23.05.02.003--
Skin striae23.01.05.002--Not Available
Telangiectasia24.03.03.003; 23.06.03.001--
Urticaria23.04.02.001; 10.01.06.001--
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