Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Gadofosveset
Drug ID BADD_D00987
Description Gadofosveset trisodium is an intravenous contrast agent used with magnetic resonance angiography(MRA), which is a non-invasive way of imaging blood vessels. The agent allows for the vascular system to be imaged more clearly by the MRA. In this way, gadofosveset trisodium is used to help diagnose certain disorders of the heart and blood vessels.
Indications and Usage Gadofosveset trisodium is indicated for use as a contrast agent in magnetic resonance angiography (MRA) to evaluate aortoiliac occlusive disease (AIOD) in adults with known or suspected peripheral vascular disease.
Marketing Status Discontinued
ATC Code V08CA11
DrugBank ID DB06705
KEGG ID D08005
MeSH ID C109932
PubChem ID 46174086
TTD Drug ID D0H0WK
NDC Product Code Not Available
Synonyms gadofosveset trisodium | gadofosveset | MS 325 | MS-325 | Vasovist
Chemical Information
Molecular Formula C33H41GdN3O14P
CAS Registry Number 193901-90-5
SMILES [H+].[H+].[H+].C1CC(CCC1OP(=O)([O-])OCC(CN(CCN(CC(=O)[O-])CC(=O)[O-])CC(=O)[O-]) N(CC(=O)[O-])CC(=O)[O-])(C2=CC=CC=C2)C3=CC=CC=C3.[Gd+3]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Connective tissue disorder15.06.01.006--Not Available
Infestation23.09.05.001; 11.09.01.001--Not Available
Malnutrition14.03.02.004--Not Available
Mediastinal disorder22.09.03.001--Not Available
Mental disorder19.07.01.002--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Inner ear disorder04.04.02.002--Not Available
Pulmonary function test decreased13.19.01.001--Not Available
Vessel puncture site bruise12.07.04.009; 08.02.04.009; 24.07.06.016; 23.03.11.014--Not Available
Anal pruritus07.03.03.002--Not Available
Anorectal discomfort07.03.03.003--Not Available
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