Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Gadodiamide
Drug ID BADD_D00985
Description Gadodiamide is a paramagnetic gadolinium-based contrast agent (GBCA) that is used in MR imaging procedures to assist in the visualization of blood vessels. It is intravenously injected and is commonly marketed under the trade name Omniscan.
Indications and Usage For intravenous use in MRI to visualize lesions with abnormal vascularity (or those thought to cause abnormalities in the blood-brain barrier) in the brain (intracranial lesions), spine, and associated tissues.
Marketing Status Prescription; Discontinued
ATC Code V08CA03
DrugBank ID DB00225
KEGG ID D04284
MeSH ID C064925
PubChem ID 60754
TTD Drug ID D03EEH
NDC Product Code 0407-0690; 0407-0691; 71806-069
Synonyms gadodiamide | Gd-DTPA bis-(methylamide) | Gd-DTPA-BMA | Omniscan | Omniscan Unique Softpack
Chemical Information
Molecular Formula C16H28GdN5O9
CAS Registry Number 122795-43-1
SMILES CNC(=O)CN(CCN(CCN(CC(=O)NC)CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].O.[Gd+3]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Ageusia17.02.07.001; 07.14.03.003--Not Available
Anaphylactoid reaction24.06.03.007; 10.01.07.003--Not Available
Arrhythmia02.03.02.001--Not Available
Arthralgia15.01.02.001--
Ataxia17.02.02.001; 08.01.02.004--
Cardiac failure02.05.01.001--
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.011--Not Available
Chills15.05.03.016; 08.01.09.001--
Coma17.02.09.001--Not Available
Coordination abnormal17.02.02.004--Not Available
Death08.04.01.001--
Diarrhoea07.02.01.001--
Dry mouth07.06.01.002--
Dysgeusia07.14.03.001; 17.02.07.003--
Dyspnoea22.02.01.004; 02.01.03.002--
Eructation07.01.02.003--
Fatigue08.01.01.002--
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Generalised tonic-clonic seizure17.12.01.002--Not Available
Hepatic function abnormal09.01.02.001--Not Available
Hyperhidrosis23.02.03.004; 08.01.03.028--
Injection site reaction12.07.03.015; 08.02.03.014--
Malaise08.01.01.003--
Melaena24.07.02.013; 07.12.02.004--Not Available
Migraine24.03.05.003; 17.14.02.001--Not Available
Multiple sclerosis17.16.01.001; 10.04.10.008--Not Available
Myalgia15.05.02.001--
Myocardial infarction24.04.04.009; 02.02.02.007--
Pain08.01.08.004--
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