Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Frovatriptan succinate
Drug ID BADD_D00977
Description Frovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular those associated with menstruation. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head.
Indications and Usage For the acute treatment of migraine attacks with or without aura in adults.
Marketing Status Prescription
ATC Code N02CC07
DrugBank ID DB00998
KEGG ID D04264
MeSH ID C108128
PubChem ID 152943
TTD Drug ID D06FPQ
NDC Product Code 76055-0008; 69238-1539; 63481-025; 66039-865; 82245-0110; 0603-3718; 68625-025; 68462-694
Synonyms frovatriptan | 3-methylamino-6-carboxamido-1,2,3,4-tetrahydrocarbazole | Frova | VML-251 | VML251 | Frovelan | SB 209509 | Allegro | frovatriptan succinate | (+)-(R)-5,6,7,8-tetrahydro-6-(methylamino)carbazole-3-carboxamide succinate (1:1), monohydrate
Chemical Information
Molecular Formula C18H25N3O6
CAS Registry Number 158930-17-7
SMILES CNC1CCC2=C(C1)C3=C(N2)C=CC(=C3)C(=O)N.C(CC(=O)O)C(=O)O.O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Abnormal dreams19.02.03.001; 17.15.02.001--Not Available
Agitation19.06.02.001; 17.02.05.012--
Amnesia19.20.01.001; 17.03.02.001--
Anxiety19.06.02.002--
Arteriospasm coronary24.04.04.005; 02.02.02.005--Not Available
Arthralgia15.01.02.001--
Asthenia08.01.01.001--Not Available
Ataxia08.01.02.004; 17.02.02.001--
Back pain15.03.04.005--
Bone pain15.02.01.001--
Bradycardia02.03.02.002--Not Available
Change of bowel habit07.02.03.002--Not Available
Cheilitis23.03.03.025; 07.05.01.001--
Chest pain02.02.02.011; 22.02.08.003; 08.01.08.002--Not Available
Chills15.05.03.016; 08.01.09.001--
Confusional state19.13.01.001; 17.02.03.005--
Conjunctivitis11.01.06.012; 06.04.01.002--
Constipation07.02.02.001--
Dehydration14.05.05.001--
Depression19.15.01.001--
Dermatitis bullous23.03.01.002--
Diarrhoea07.02.01.001--
Disturbance in attention17.03.03.001; 19.21.02.002--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dry mouth07.06.01.002--
Dysaesthesia17.02.06.003--
Dysgeusia17.02.07.003; 07.14.03.001--
Dyspepsia07.01.02.001--
Dysphagia07.01.06.003--
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