Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Frovatriptan
Drug ID BADD_D00976
Description Frovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular those associated with menstruation. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head.
Indications and Usage For the acute treatment of migraine attacks with or without aura in adults.
Marketing Status Prescription
ATC Code N02CC07
DrugBank ID DB00998
KEGG ID D07997
MeSH ID C108128
PubChem ID 77992
TTD Drug ID D06FPQ
NDC Product Code 0378-3140
Synonyms frovatriptan | 3-methylamino-6-carboxamido-1,2,3,4-tetrahydrocarbazole | Frova | VML-251 | VML251 | Frovelan | SB 209509 | Allegro | frovatriptan succinate | (+)-(R)-5,6,7,8-tetrahydro-6-(methylamino)carbazole-3-carboxamide succinate (1:1), monohydrate
Chemical Information
Molecular Formula C14H17N3O
CAS Registry Number 158747-02-5
SMILES CNC1CCC2=C(C1)C3=C(N2)C=CC(=C3)C(=O)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Tension19.06.02.005--Not Available
Thinking abnormal19.10.03.001; 17.02.05.023--Not Available
Thirst08.01.09.021; 14.03.02.007--Not Available
Throat tightness22.02.05.015; 19.01.02.005--Not Available
Tinnitus17.04.07.004; 04.04.01.002--
Tongue paralysis17.04.09.001; 07.14.02.012--Not Available
Toothache07.09.06.001--
Tremor17.01.06.002--
Urethral disorder20.07.01.002--Not Available
Urinary tract disorder20.08.01.001--Not Available
Urine abnormality20.02.01.013--Not Available
Vascular purpura24.07.06.011; 23.06.01.008; 01.01.04.007--Not Available
Vasospasm24.04.02.002--Not Available
Ventricular fibrillation02.03.04.008--
Ventricular tachycardia02.03.04.010--
Vertigo17.02.12.002; 04.04.01.003--
Visual impairment06.02.06.008--Not Available
Vomiting07.01.07.003--
Muscle tightness15.05.03.007--Not Available
Acute coronary syndrome24.04.04.011; 02.02.02.015--Not Available
Musculoskeletal discomfort15.03.04.001--Not Available
Affect lability19.04.01.001--Not Available
Haemorrhage24.07.01.002--Not Available
Muscle relaxant therapy25.16.01.001--Not Available
Urine output increased13.13.03.002--Not Available
Hot flush24.03.01.005; 08.01.03.027; 21.02.02.001--
Malnutrition14.03.02.004--Not Available
Mental disorder19.07.01.002--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Ill-defined disorder08.01.03.049--Not Available
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