Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Fosinoprilat
Drug ID BADD_D00969
Description Fosinoprilat is the active phosphinic acid metabolite of prodrug [fosinopril], which is activated by esterases in vivo. It binds zinc with phosphinic acid group.
Indications and Usage Not Available
Marketing Status experimental
ATC Code Not Available
DrugBank ID DB14207
KEGG ID D03772
MeSH ID C046965
PubChem ID 62956
TTD Drug ID Not Available
NDC Product Code Not Available
UNII S312EY6ZT8
Synonyms fosinoprilat | fosinoprilic acid | fosfenopril | SQ 27519 | SQ-27519 | SQ-27,519
Chemical Information
Molecular Formula C23H34NO5P
CAS Registry Number 95399-71-6
SMILES C1CCC(CC1)C2CC(N(C2)C(=O)CP(=O)(CCCCC3=CC=CC=C3)O)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Agranulocytosis01.02.03.001--Not Available
Anaemia01.03.02.001--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Anaphylactoid reaction24.06.03.007; 10.01.07.003--Not Available
Angina pectoris02.02.02.002; 24.04.04.002--
Angioedema22.04.02.008; 23.04.01.001; 10.01.05.0090.123772%Not Available
Arrhythmia02.03.02.001--Not Available
Arrhythmia supraventricular02.03.03.001--Not Available
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Asthenia08.01.01.001--Not Available
Blood pressure increased13.14.03.005--Not Available
Body temperature increased13.15.01.001--Not Available
Bradycardia02.03.02.002--Not Available
Bronchospasm22.03.01.004; 10.01.03.012--
Cardiac arrest02.03.04.001--
Cardio-respiratory arrest22.02.06.007; 02.03.04.002--Not Available
Cerebral infarction17.08.01.004; 24.04.06.002--Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.0070.014065%
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.011--Not Available
Conduction disorder02.03.01.008--
Confusional state17.02.03.005; 19.13.01.001--
Constipation07.02.02.001--
Cough22.02.03.001--
Dermatitis23.03.04.002--Not Available
Dermatitis exfoliative23.03.07.001; 10.01.01.0040.007032%
Diarrhoea07.02.01.001--
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.0030.007032%
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