| Drug Name |
Formoterol |
| Drug ID |
BADD_D00958 |
| Description |
Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001.[L10986] It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers.[A189528] A major clinical advantage of formoterol over other inhaled beta-agonists is its rapid onset of action (2-3 minutes), which is at least as fast as [salbutamol], combined with a long duration of action (12 hours) - for this reason, treatment guidelines for asthma recommend its use as both a reliever and maintenance medication.[L11256] It is available as a single-entity product[L10986,L11223] and in several formulations in combination with both inhaled corticosteroids[L10995,L10619] and long-acting muscarinic antagonists.[L10992,L10989] |
| Indications and Usage |
For use as long-term maintenance treatment of asthma in patients 6 years of age and older with reversible obstructive airways disease, including patients with symptoms of nocturnal asthma, who are using optimal corticosteroid treatment and experiencing regular or frequent breakthrough symptoms requiring use of a short-acting bronchodilator. Not indicated for asthma that can be successfully managed with occasional use of an inhaled, short-acting beta2-adrenergic agonist. Also used for the prevention of exercise-induced bronchospasm, as well as long-term treatment of bronchospasm associated with COPD. |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
R03AC13; R03CC15 |
| DrugBank ID |
DB00983
|
| KEGG ID |
D07990
|
| MeSH ID |
D000068759
|
| PubChem ID |
3410
|
| TTD Drug ID |
D04KJO
|
| NDC Product Code |
Not Available |
| Synonyms |
Formoterol Fumarate | Formoterol Fumarate, ((R*,R*)-(+-))-isomer | 3-Formylamino-4-hydroxy-alpha-(N-1-methyl-2-p-methoxyphenethylaminomethyl)benzyl alcohol.hemifumarate | BD 40A | Formoterol | Eformoterol | Oxis | Arformoterol | Formoterol, ((R*,R*)-(+-))-isomer | Foradil |
