Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Flunisolide hemihydrate
Drug ID BADD_D00921
Description Flunisolide (marketed as AeroBid, Nasalide, Nasarel) is a corticosteroid with anti-inflammatory actions. It is often prescribed as treatment for allergic rhinitis and its principle mechanism of action involves activation of glucocorticoid receptors.
Indications and Usage For the maintenance treatment of asthma as a prophylactic therapy.
Marketing Status approved; investigational
ATC Code R01AD04; R03BA03
DrugBank ID DB00180
KEGG ID D00324; D04214
MeSH ID C007734
PubChem ID 82153
TTD Drug ID D0FM2P
NDC Product Code 46439-8740; 51927-1794; 50742-317; 24208-344
UNII 78M02AA8KF
Synonyms flunisolide | flunisolide anhydrous | 6alpha-fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16, 17-acetal with acetone | 6 alpha-fluorodihydroxy-16 alpha,17 alpha-isopropylidenedioxy-1,4-pregnadiene-3,20- dione | flunisolide hemihydrate | flunisolide hemihydrate, (6alpha,11beta,16alpha)-isomer | Nasarel | AeroBid | Aerospan | RS-3999 | Nasalide | flunisolide acetate | RS-1320 | RS1320 | flunisolide 21-acetate | flunisolide, (6beta,11beta,16alpha)-isomer | ratio-Flunisolide | Rhinalar | Syntaris | flunisolide HFA | flunisolide hydrofluoroalkane | Apo-Flunisolide | Inhacort
Chemical Information
Molecular Formula C24H31FO6
CAS Registry Number 3385-03-3
SMILES CC1(OC2CC3C4CC(C5=CC(=O)C=CC5(C4C(CC3(C2(O1)C(=O)CO)C)O)C)F)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Oedema peripheral14.05.06.011; 08.01.07.007; 02.05.04.007--
Oral candidiasis11.03.03.004; 07.05.07.001--Not Available
Pain08.01.08.004--
Palpitations02.11.04.012--
Pharyngitis11.01.13.003; 07.05.07.004; 22.07.03.004--
Pleurisy22.05.01.001--Not Available
Pneumonia22.07.01.003; 11.01.09.003--Not Available
Productive cough22.02.03.005--
Pruritus23.03.12.001--
Psychomotor hyperactivity19.11.02.003; 17.01.02.011--Not Available
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Rhinitis22.07.03.006; 11.01.13.004--
Rhinorrhoea22.12.03.021--
Sinus congestion22.04.06.001--Not Available
Sinusitis22.07.03.007; 11.01.13.005--
Sneezing22.12.03.024--
Stomatitis07.05.06.005--
Tachycardia02.03.02.007--Not Available
Throat irritation22.12.03.029; 07.05.05.037--Not Available
Tremor17.01.06.002--
Upper respiratory tract infection22.07.03.011; 11.01.13.009--
Urinary tract infection20.08.02.001; 11.01.14.004--
Urticaria23.04.02.001; 10.01.06.001--
Vaginal infection21.14.02.002; 11.01.10.002--
Vertigo17.02.12.002; 04.04.01.003--
Vision blurred17.17.01.010; 06.02.06.007--
Vomiting07.01.07.003--
Weight increased13.15.01.006--
Wheezing22.03.01.009--
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