| Drug Name |
Fludrocortisone acetate |
| Drug ID |
BADD_D00918 |
| Description |
Fludrocortisone is a synthetic mineralocorticoid used in conjunction with [hydrocortisone] to replace missing endogenous corticosteroids in patients with adrenal insufficiency.[A187169,A187187] It is functionally similar to [aldosterone], the body's primary endogenous mineralocorticoid, and is structurally analogous to [cortisol], differing only by a fluorine atom at the 9-position of the steroid structure - this fluorination is thought to be crucial to fludrocortisone's significant mineralocorticoid potency.[A5423] |
| Indications and Usage |
For partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease and for the treatment of salt-losing adrenogenital syndrome. |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
H02AA02 |
| DrugBank ID |
DB00687
|
| KEGG ID |
D00986
|
| MeSH ID |
C034635
|
| PubChem ID |
225609
|
| TTD Drug ID |
Not Available
|
| NDC Product Code |
69238-7033; 68084-288; 58159-074; 0115-7033; 55154-6645; 42291-764; 49452-3155; 51927-2408; 50268-330; 63629-8806; 71335-0976; 63629-7780; 14096-127; 42291-529; 46439-8721; 0615-6562; 38779-0129; 65089-0015; 62991-2773; 0555-0997 |
| Synonyms |
fludrocortisone acetate | fluorocortisol acetate | fludrocortisone 21-acetate | 9 alpha-fluorocortisol acetate | Florinef | Cortineff |
