Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Florbetaben f-18
Drug ID BADD_D00905
Description Florbetaben is a fluorine-18 (18F)-labeled stilbene derivative used for Positron Emission Tomography (PET) imaging of the brain. It is used for the non-invasive detection of the density of ß-amyloid neuritic plaques in the brain of adult patients with cognitive impairment.
Indications and Usage Florbetaben is a radioactive diagnostic agent indicated for Positron Emission Tomography (PET) imaging of the brain to estimate β-amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer’s Disease (AD) and other causes of cognitive decline.
Marketing Status Not Available
ATC Code V09AX06
DrugBank ID DB09148
KEGG ID D10002
MeSH ID C527756
PubChem ID 11501341
TTD Drug ID Not Available
NDC Product Code Not Available
Synonyms 4-(N-methylamino)-4'-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)stilbene | florbetaben | BAY94 9172 | BAY94-9172 | BAY 94-9172 | 18F-florbetaben | 18F-BAY94-9172
Chemical Information
Molecular Formula C21H26FNO3
CAS Registry Number 902143-01-5
SMILES CNC1=CC=C(C=C1)C=CC2=CC=C(C=C2)OCCOCCOCCF
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Application site erythema08.02.01.001; 23.03.06.005; 12.07.01.001--Not Available
Erythema23.03.06.001--Not Available
Injection site erythema23.03.06.015; 12.07.03.001; 08.02.03.001--Not Available
Injection site irritation12.07.03.027; 08.02.03.027--Not Available
Injection site pain12.07.03.011; 08.02.03.010--Not Available
Injection site reaction12.07.03.015; 08.02.03.014--
Pain08.01.08.004--
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