Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Flavoxate
Drug ID BADD_D00900
Description A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. [PubChem]
Indications and Usage For symptomatic relief of dysuria, urgency, nocturia, suprapubic pain, frequency and incontinence as may occur in cystitis, prostatitis, urethritis, urethrocystitis/urethrotrigonitis.
Marketing Status Prescription; Discontinued
ATC Code G04BD02
DrugBank ID DB01148
KEGG ID D07961
MeSH ID D005422
PubChem ID 3354
TTD Drug ID D0ND2J
NDC Product Code Not Available
Synonyms Flavoxate | Flavoxate Hydrochloride | Hydrochloride, Flavoxate | Urispas | Uronid | Bladuril | Spasuret
Chemical Information
Molecular Formula C24H25NO4
CAS Registry Number 15301-69-6
SMILES CC1=C(OC2=C(C1=O)C=CC=C2C(=O)OCCN3CCCCC3)C4=CC=CC=C4
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Confusional state19.13.01.001; 17.02.03.005--
Dry mouth07.06.01.002--
Eosinophilia01.02.04.001--
Feeling abnormal08.01.09.014--Not Available
Headache17.14.01.001--
Hyperpyrexia08.05.02.002--Not Available
Leukopenia01.02.02.001--Not Available
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Palpitations02.01.02.003--
Skin disorder23.03.03.007--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Tachycardia02.03.02.007--Not Available
Tension19.06.02.005--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vertigo17.02.12.002; 04.04.01.003--
Vision blurred17.17.01.010; 06.02.06.007--
Vomiting07.01.07.003--
Dermatosis23.03.03.017--Not Available
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