| Drug Name |
Fexofenadine hydrochloride |
| Drug ID |
BADD_D00894 |
| Description |
Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms.[L4269] It is selective for the H1 receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier[L10779] - this is in contrast to previous first-generation antihistamines, such as [diphenhydramine], which readily bind to off-targets that contribute to side effects such as sedation.[A1452] Fexofenadine is the major active metabolite of [terfenadine][A1495] and is administered as a racemic mixture in which both enantiomers display approximately equivalent antihistamine activity.[L10779] |
| Indications and Usage |
For management of Seasonal allergic rhinitis |
| Marketing Status |
Prescription; OTC; Discontinued |
| ATC Code |
R06AX26 |
| DrugBank ID |
DB00950
|
| KEGG ID |
D00671
|
| MeSH ID |
C093230
|
| PubChem ID |
63002
|
| TTD Drug ID |
D01KPV
|
| NDC Product Code |
55111-783; 70518-2971; 58602-710; 55301-847; 11673-617; 62011-0409; 50594-769; 68016-995; 46438-0638; 62207-765; 0113-0847; 51686-0001; 66577-021; 63868-334; 41167-4122; 69848-002; 69842-052; 62756-542; 12579-182; 46122-462; 62993-0809; 58175-0616; 63868-025; 43598-809; 68196-107; 63940-769; 50090-1234; 36800-653; 72036-192; 71796-015; 54257-170; 41163-292; 12579-189; 49348-968; 73581-011; 65862-966; 68016-176; 68016-887; 62756-545; 53104-7583; 68998-192; 49035-995; 55111-782; 57344-192; 72969-028; 11822-0425; 79481-0847; 61919-536; 36800-652; 46122-387; 65096-0103; 51927-0044; 41167-4244; 68210-2210; 53360-1109; 72476-847; 45802-571; 41250-784; 51672-2121; 73581-103; 36800-954; 53943-392; 68016-769; 21130-784; 68210-0122; 17404-0019; 41163-571; 51672-2119; 46438-1111; 11673-571; 68071-5191; 44657-0078; 0363-0097; 0480-7253; 49035-366; 55111-784; 68001-440; 36800-691; 0363-0783; 68001-439; 69842-492; 55111-023; 45802-847; 51927-0016; 56062-847; 64679-982; 12579-188; 68998-292; 63981-847; 70000-0586; 62011-0413; 55910-571; 63981-571; 65372-1167; 60000-409; 46438-0107; 12854-915; 43598-054; 70000-0361; 11822-3698; 52904-190; 77777-113; 71335-0721; 62207-766; 10202-229; 62756-543; 68071-2504; 41167-4131; 65977-0060; 70677-0074; 46438-0651; 49035-784; 58602-711; 0363-0784; 68391-847; 41167-4124; 72288-847; 0363-0095; 37808-571; 11822-0571; 70518-1702; 68071-1896; 63187-334; 67751-033; 82348-104; 41167-4120; 36800-319; 65015-894; 64679-744; 53943-021; 55319-917; 66715-9707; 64679-987; 71610-292; 41167-4232; 72036-292; 0480-7252; 43598-936; 0363-9898; 72476-192; 0113-0571; 41167-4121; 53360-1106; 46438-0637; 55910-111; 55315-355; 63868-667; 37808-847; 62207-002; 54257-001; 68210-4090; 71335-0483; 57344-292; 43598-577; 43063-337; 63940-768; 68196-976; 71309-091; 70692-134; 53943-192; 30142-878; 10202-107; 0904-6711; 54257-702; 70518-1218 |
| Synonyms |
fexofenadine | alpha-(4-(1-carboxy-1-methylethyl)phenyl)-4-hydroxydiphenylmethyl-1-piperidinebutanol | fexofenadine hydrochloride | MDL 16.455 | MDL-16455 | MDL 16455 | Allegra | Telfast | MDL 16,455A |
