Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ferric carboxymaltose
Drug ID BADD_D00882
Description Ferric Carboxymaltose is an iron replacement product and chemically, an iron carbohydrate complex. FDA approved on July 25, 2013.
Indications and Usage Ferric carboxymaltose is a iron replacement product indicated for the treatment of iron deficiency anemia in adult patients who have intolerance to oral iron or have had unsatisfactory response to oral iron or those who have non-dialysis dependent chronic kidney disease.
Marketing Status Prescription
ATC Code Not Available
DrugBank ID DB08917
KEGG ID D08920
MeSH ID C522335
PubChem ID 86278165
TTD Drug ID D02ICI
NDC Product Code 59353-363; 64552-4070; 0517-0620; 42973-330; 14593-923
Synonyms ferric carboxymaltose | iron carboxymaltose | iron dextri-maltose | polynuclear iron (III)-hydroxide 4(R)-(poly-(1->4)-o-alpha-D-glucopyranosyl)-oxy-2(R),3(S),5(R), 6-tetrahydroxy-hexanoate | Ferinject | VIT-45 | VIT 45 | injectafer
Chemical Information
Molecular Formula C24H44FeO25-
CAS Registry Number 9007-72-1
SMILES C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)OC(C(CO)O)C(C(C(=O)[O-])O)O)CO)CO )O)O)O)O.O.[OH-].[O-2].[Fe+3]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hypoaesthesia oral07.05.05.003; 17.02.06.021-Not Available
Paraesthesia oral17.02.06.008; 07.05.03.003-Not Available
Laboratory test13.18.01.005--Not Available
Hepatic enzyme increased13.03.01.019-Not Available
Hot flush08.01.03.027; 24.03.01.005; 21.02.02.001-
Limb discomfort15.03.04.014-Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Ill-defined disorder08.01.03.049-Not Available
Sensation of foreign body08.01.09.002-Not Available
Drug intolerance08.06.01.013--Not Available
Iron overload14.13.03.002; 12.02.08.005-
Oncogenic osteomalacia16.32.01.005; 15.02.03.012; 14.04.04.012--Not Available
Impaired self-care19.01.02.014; 08.01.03.071-Not Available
Pharyngeal paraesthesia22.04.05.018; 17.02.06.035-Not Available
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