Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ferric carboxymaltose
Drug ID BADD_D00882
Description Ferric Carboxymaltose is an iron replacement product and chemically, an iron carbohydrate complex. FDA approved on July 25, 2013.
Indications and Usage Ferric carboxymaltose is a iron replacement product indicated for the treatment of iron deficiency anemia in adult patients who have intolerance to oral iron or have had unsatisfactory response to oral iron or those who have non-dialysis dependent chronic kidney disease.
Marketing Status Prescription
ATC Code Not Available
DrugBank ID DB08917
KEGG ID D08920
MeSH ID C522335
PubChem ID 86278165
TTD Drug ID D02ICI
NDC Product Code 59353-363; 64552-4070; 0517-0620; 42973-330; 14593-923
Synonyms ferric carboxymaltose | iron carboxymaltose | iron dextri-maltose | polynuclear iron (III)-hydroxide 4(R)-(poly-(1->4)-o-alpha-D-glucopyranosyl)-oxy-2(R),3(S),5(R), 6-tetrahydroxy-hexanoate | Ferinject | VIT-45 | VIT 45 | injectafer
Chemical Information
Molecular Formula C24H44FeO25-
CAS Registry Number 9007-72-1
SMILES C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)OC(C(CO)O)C(C(C(=O)[O-])O)O)CO)CO )O)O)O)O.O.[OH-].[O-2].[Fe+3]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Lip swelling23.04.01.007; 10.01.05.005; 07.05.04.005-Not Available
Loss of consciousness17.02.04.004-Not Available
Malaise08.01.01.003--
Migraine24.03.05.003; 17.14.02.001-Not Available
Movement disorder17.01.02.010-Not Available
Muscle spasms15.05.03.004-
Muscular weakness17.05.03.005; 15.05.06.001--
Musculoskeletal pain15.03.04.007-
Myalgia15.05.02.001-
Myocardial infarction24.04.04.009; 02.02.02.007--
Nausea07.01.07.001-
Oedema peripheral14.05.06.011; 08.01.07.007; 02.05.04.007--
Osteomalacia15.02.03.001; 20.01.01.002; 14.04.04.001-Not Available
Oxygen saturation decreased13.02.01.004-Not Available
Pain08.01.08.004-
Pain in extremity15.03.04.010-
Pain in jaw15.02.01.003-Not Available
Palpitations02.01.02.003-
Paraesthesia17.02.06.005-
Pharyngeal oedema22.04.05.003; 10.01.05.016; 23.04.01.016-Not Available
Phlebitis24.05.03.001; 12.02.01.002-
Presyncope24.06.02.010; 17.02.05.009; 02.01.02.007-
Pruritus23.03.12.001-
Pulse absent13.14.04.005-Not Available
Pyrexia08.05.02.003-
Rash23.03.13.001-Not Available
Rash erythematous23.03.06.003-Not Available
Rash generalised23.03.13.002-Not Available
Rash macular23.03.13.003-Not Available
Rash pruritic23.03.12.002-Not Available
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