Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ferric carboxymaltose
Drug ID BADD_D00882
Description Ferric Carboxymaltose is an iron replacement product and chemically, an iron carbohydrate complex. FDA approved on July 25, 2013.
Indications and Usage Ferric carboxymaltose is a iron replacement product indicated for the treatment of iron deficiency anemia in adult patients who have intolerance to oral iron or have had unsatisfactory response to oral iron or those who have non-dialysis dependent chronic kidney disease.
Marketing Status Prescription
ATC Code Not Available
DrugBank ID DB08917
KEGG ID D08920
MeSH ID C522335
PubChem ID 86278165
TTD Drug ID D02ICI
NDC Product Code 59353-363; 64552-4070; 0517-0620; 42973-330; 14593-923
Synonyms ferric carboxymaltose | iron carboxymaltose | iron dextri-maltose | polynuclear iron (III)-hydroxide 4(R)-(poly-(1->4)-o-alpha-D-glucopyranosyl)-oxy-2(R),3(S),5(R), 6-tetrahydroxy-hexanoate | Ferinject | VIT-45 | VIT 45 | injectafer
Chemical Information
Molecular Formula C24H44FeO25-
CAS Registry Number 9007-72-1
SMILES C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)OC(C(CO)O)C(C(C(=O)[O-])O)O)CO)CO )O)O)O)O.O.[OH-].[O-2].[Fe+3]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Dysgeusia17.02.07.003; 07.14.03.001--
Dyspepsia07.01.02.001-
Dyspnoea22.02.01.004; 02.01.03.002-
Epistaxis22.04.03.001; 24.07.01.005--
Erythema23.03.06.001-Not Available
Extravasation08.01.03.008-Not Available
Eye swelling06.08.03.003-Not Available
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014-Not Available
Feeling hot08.01.09.009-Not Available
Flank pain15.03.04.003; 08.01.08.007; 20.02.03.006-
Flushing08.01.03.025; 24.03.01.002; 23.06.05.003-
Gait disturbance17.02.05.016; 08.01.02.002--
Gamma-glutamyltransferase increased13.03.01.011--
Gastrooesophageal reflux disease07.02.02.003--
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005-
Haemoglobin decreased13.01.05.003-Not Available
Head discomfort17.02.05.027-Not Available
Headache17.14.01.001-
Heart rate increased13.14.04.002-Not Available
Hyperhidrosis23.02.03.004; 08.01.03.028-
Hypersensitivity10.01.03.003-
Hypertension24.08.02.001-
Hypoaesthesia17.02.06.023-Not Available
Hypophosphataemia14.04.03.001-
Hypotension24.06.03.002-
Influenza like illness08.01.03.010-
Injection site irritation08.02.03.027; 12.07.03.027--Not Available
Injection site pain12.07.03.011; 08.02.03.010--Not Available
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