Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Fenoprofen
Drug ID BADD_D00877
Description An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Indications and Usage For relief of the signs and symptoms of rheumatoid arthritis and osteoarthritis. Also for the relief of mild to moderate pain.
Marketing Status Prescription; Discontinued
ATC Code M01AE04
DrugBank ID DB00573
KEGG ID D02350
MeSH ID D005279
PubChem ID 3342
TTD Drug ID D03XYW
NDC Product Code Not Available
Synonyms Fenoprofen | Fenoprofen Dihydrate, Calcium Salt | Nalgesic | Fenoprofen Calcium | Fenoprofen, Anhydrous, Calcium Salt | Nalfon
Chemical Information
Molecular Formula C15H14O3
CAS Registry Number 29679-58-1
SMILES CC(C1=CC(=CC=C1)OC2=CC=CC=C2)C(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Agranulocytosis01.02.03.001--Not Available
Alopecia23.02.02.001--
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Angioedema23.04.01.001; 10.01.05.009--Not Available
Anuria20.01.03.002--Not Available
Aphthous ulcer07.05.06.002--Not Available
Aplastic anaemia01.03.03.002--Not Available
Aspartate aminotransferase13.03.01.032--Not Available
Asthenia08.01.01.001--Not Available
Atrial fibrillation02.03.03.002--
Azotaemia20.01.01.001--Not Available
Bladder pain20.02.02.001--Not Available
Blood lactate dehydrogenase13.04.02.009--Not Available
Body temperature increased13.15.01.001--Not Available
Breast pain21.05.05.003--
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001--
Cystitis20.03.02.002; 11.01.14.001--
Depression19.15.01.001--
Dermatitis23.03.04.002--Not Available
Dermatitis exfoliative23.03.07.001; 10.01.01.004--
Diarrhoea07.02.01.001--
Diplopia17.17.01.005; 06.02.06.002--Not Available
Discomfort08.01.08.003--Not Available
Disorientation19.13.01.002; 17.02.05.015--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dry mouth07.06.01.002--
Dysgeusia07.14.03.001; 17.02.07.003--
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