Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Fenofibrate
Drug ID BADD_D00873
Description Fenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil].[A185954] Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia.[L8588,L8591] Fenofibrate was granted FDA approval on 31 December 1993.[L8585]
Indications and Usage For use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb)
Marketing Status Prescription; Discontinued
ATC Code C10AB05
DrugBank ID DB01039
KEGG ID D00565
MeSH ID D011345
PubChem ID 3339
TTD Drug ID D07XGR
NDC Product Code 68180-746; 0378-3065; 0115-0522; 46708-555; 27241-117; 71335-0891; 0115-1523; 68071-2587; 13672-020; 13668-439; 62332-361; 70934-567; 27241-116; 62332-555; 42291-292; 66869-137; 51407-094; 68543-3189; 0074-3189; 0378-3066; 16714-741; 46708-086; 31722-596; 70934-508; 68180-745; 65862-769; 71610-027; 16714-163; 50090-3044; 0378-7100; 0904-6810; 60505-3120; 51407-204; 42385-950; 66064-1006; 71335-1286; 71205-366; 50090-5401; 68180-130; 55111-395; 27241-120; 68071-2540; 71205-949; 62559-461; 69238-1261; 31722-595; 62559-305; 0378-7101; 50090-5796; 0115-0511; 43975-305; 50268-313; 42858-067; 68071-4692; 0904-7128; 68071-4992; 70518-3370; 62332-554; 68382-269; 43547-430; 35561-347; 63304-901; 27437-109; 16714-162; 17337-0410; 69238-1262; 62332-351; 68294-0001; 70518-2907; 43975-444; 50090-1275; 63304-449; 62332-539; 55111-349; 68180-231; 70518-2947; 51407-205; 59651-203; 59651-201; 62332-085; 62332-350; 63187-681; 69844-008; 42385-935; 68071-4983; 63304-444; 65862-768; 69097-458; 70966-0021; 68788-7579; 68180-360; 68382-270; 13668-438; 72189-172; 68071-3114; 68071-4310; 68462-581; 50090-4121; 71205-050; 50090-5854; 46708-351; 59349-0018; 62559-306; 50090-1274; 71335-0741; 69097-894; 60687-629; 42858-200; 69097-895; 35561-345; 68084-835; 46708-085; 60687-618; 68071-4358; 0074-3173; 51079-608; 50090-5327; 68788-7932; 63629-7213; 13668-440; 51407-091; 51407-092; 35561-346; 60760-411; 62332-360; 50090-3887; 50090-3842; 69238-1263; 51079-599; 68071-1601; 68084-827; 63629-2505; 42291-290; 70934-638; 70518-0700; 42858-660; 27241-118; 11014-0132; 71205-190; 68071-4264; 42385-951; 50268-309; 71335-1292; 71335-1756; 59651-202; 63629-1514; 68012-490; 0115-1522; 50090-4957; 49452-3101; 70756-214; 69844-013; 0378-4390; 16714-739; 68071-4320; 42385-936; 68084-329; 46708-857; 68071-5101; 63629-1099; 0904-7161; 68180-232; 63187-760; 46708-554; 50090-4698; 50090-3373; 46708-350; 27437-108; 46708-084; 0615-8270; 62332-086; 68788-8106; 17337-0019; 70934-223; 50090-2899; 68071-4182; 66869-147; 16714-740; 68180-131; 63187-640; 60760-318; 45802-315; 50268-312; 43353-898; 68084-328; 43598-910; 68543-3173; 70756-215; 51407-090; 72189-026; 62332-538; 17337-0430; 69367-257; 68012-495; 46708-361; 68462-582; 68682-495; 62332-084; 60760-660; 63304-443; 42291-289; 43598-909; 70518-2768; 43547-431; 27437-107; 0115-0533; 62559-460; 70934-224; 55700-876; 68071-4991; 11722-065; 50090-5244; 65977-0074; 70934-591; 63629-1100; 45802-132; 0378-4391; 69844-012; 69367-254; 42858-454; 68788-7662; 69367-269; 63629-1101; 27241-119; 71335-0872; 68180-389; 68071-4289; 60505-3121; 71335-2016; 50090-4031; 69367-270; 68180-363; 43353-272; 63187-940; 68071-2369; 69844-009; 69097-459; 50090-3904; 68180-362; 27437-110; 68084-635; 63304-448; 69097-896; 42858-134; 50090-2546; 58175-0348; 71335-1701; 69238-1260; 46708-360; 0115-5511; 63304-900; 0115-5522; 11014-0131; 68788-7578; 43353-001; 43975-306; 50090-5158; 51407-093; 68180-361; 69367-268; 53747-033; 68682-490; 68462-580; 70518-2349; 68071-4988; 68788-7816; 70518-1988; 68180-388
Synonyms Fenofibrate | Phenofibrate | Procetofene | Procetofen | Apo-Feno-Micro | Apo Feno Micro | Apo-Fenofibrate | Apo Fenofibrate | CiL | Controlip | durafenat | Fenobeta | Fenofanton | Fenofibrat AbZ | Fenofibrat AL | Fenofibrat AZU | AZU, Fenofibrat | Fenofibrat Heumann | Heumann, Fenofibrat | Fenofibrat Hexal | Hexal, Fenofibrat | Fenofibrat Stada | Stada, Fenofibrat | fenofibrat von ct | Fenofibrat-ratiopharm | Fenofibrat ratiopharm | Fénofibrate MSD | Gen-Fenofibrate | Gen Fenofibrate | LF-178 | LF 178 | LF178 | Lipanthyl | Lipantil | Fenofibrat FPh | Lipidil | Secalip | Supralip | Fénofibrate Debat | Debat, Fénofibrate | Lipidil-Ter | Lipidil Ter | Liparison | Livesan | Lofibra | MTW-Fenofibrat | MTW Fenofibrat | Novo-Fenofibrate | Novo Fenofibrate | Nu-Fenofibrate | Nu Fenofibrate | PMS-Fenofibrate Micro | PMS Fenofibrate Micro | Tricor | Normalip | Antara Micronized Procetofen | Micronized Procetofen, Antara | Procetofen, Antara Micronized
Chemical Information
Molecular Formula C20H21ClO4
CAS Registry Number 49562-28-9
SMILES CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Cyst16.02.02.002; 08.03.05.001--Not Available
Cystitis11.01.14.001; 20.03.02.002--
Depression19.15.01.001--
Dermatitis23.03.04.002--Not Available
Dermatitis allergic23.03.04.003; 10.01.03.014--Not Available
Dermatitis atopic10.01.04.004; 23.03.04.016--Not Available
Dermatitis bullous23.03.01.002--
Dermatitis contact23.03.04.004; 12.03.01.040; 10.01.01.003--Not Available
Diabetes mellitus14.06.01.001; 05.06.01.001--Not Available
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Disorientation17.02.05.015; 19.13.01.0020.000173%Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Drug abuse19.07.02.010--Not Available
Drug eruption23.03.05.001; 10.01.01.005; 08.01.06.0150.000173%Not Available
Drug hypersensitivity10.01.01.0010.003537%Not Available
Drug interaction08.06.03.001--Not Available
Dry eye06.08.02.0010.000173%
Dry mouth07.06.01.002--
Dry skin23.03.03.0010.000173%
Duodenal ulcer07.04.02.002--
Dyspepsia07.01.02.0010.000173%
Dysphagia07.01.06.003--
Dysphonia19.19.03.002; 17.02.08.004; 22.02.05.0050.000259%
Dyspnoea22.02.01.004; 02.01.03.002--
Dysuria20.02.02.002--
Ear pain04.03.01.003--
Ecchymosis24.07.06.002; 23.06.01.001; 01.01.03.001--Not Available
Eczema23.03.04.0060.000173%
Electrocardiogram abnormal13.14.05.001--Not Available
The 3th Page    First    Pre   3 4 5 6 7    Next   Last    Total 11 Pages