Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Etonogestrel
Drug ID BADD_D00852
Description Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel.[A37184] The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.[L5692]
Indications and Usage For use as a female contraceptive (depot).
Marketing Status Prescription; Discontinued
ATC Code G03AC08
DrugBank ID DB00294
KEGG ID D04104
MeSH ID C044815
PubChem ID 6917715
TTD Drug ID D02KIU
NDC Product Code 65089-0053; 64918-1500; 60870-0475; 78206-145; 71161-147; 63190-0480; 63190-0260; 45541-1192; 64918-1906
Synonyms etonogestrel | 13-ethyl-17-hydroxy-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one | 3-oxodesogestrel | 3-ketodesogestrel | 3-oxo desogestrel | 18,19-dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-11-methylene-, (17-alpha)- | 3-keto-desogestrel | ORG-3236 | Implanon | nexplanon
Chemical Information
Molecular Formula C22H28O2
CAS Registry Number 54048-10-1
SMILES CCC12CC(=C)C3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Feeling hot08.01.09.0090.004125%Not Available
Fibroadenoma of breast21.05.01.005; 16.14.01.001--Not Available
Fibrosis08.03.01.0010.003300%Not Available
Flatulence07.01.04.002--
Fluid retention14.05.06.002; 20.01.02.003--Not Available
Fungal infection11.03.05.001--Not Available
Furuncle23.09.01.004; 11.02.05.0080.002062%Not Available
Galactorrhoea21.05.02.002; 05.03.04.0020.005362%Not Available
Gallbladder disorder09.03.02.0010.002887%Not Available
Gastritis07.08.02.001--
Gastrooesophageal reflux disease07.02.02.003--
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.0050.000825%
Generalised oedema14.05.06.007; 08.01.07.004--
Generalised tonic-clonic seizure17.12.01.002--Not Available
Gestational diabetes18.02.04.001; 14.06.01.008; 05.06.01.0080.001237%Not Available
Groin pain15.03.02.0040.000825%Not Available
Haematemesis24.07.02.011; 07.12.02.002--Not Available
Haematochezia07.12.02.003; 24.07.02.012--Not Available
Haematoma24.07.01.001--
Haemoglobin13.01.05.018--Not Available
Haemoglobin decreased13.01.05.003--Not Available
Haemoptysis24.07.01.006; 22.02.03.004; 02.01.02.006--Not Available
Haemorrhagic disorder24.07.01.021; 01.01.03.0040.001237%Not Available
Haemorrhagic stroke24.07.04.014; 17.08.01.011--Not Available
Hair colour changes23.02.06.001--
Hair growth abnormal23.02.06.0060.001650%Not Available
Hallucination19.10.02.002--
Hallucination, auditory19.10.02.003--Not Available
Headache17.14.01.0010.193027%
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