Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Etonogestrel
Drug ID BADD_D00852
Description Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel.[A37184] The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.[L5692]
Indications and Usage For use as a female contraceptive (depot).
Marketing Status Prescription; Discontinued
ATC Code G03AC08
DrugBank ID DB00294
KEGG ID D04104
MeSH ID C044815
PubChem ID 6917715
TTD Drug ID D02KIU
NDC Product Code 65089-0053; 64918-1500; 60870-0475; 78206-145; 71161-147; 63190-0480; 63190-0260; 45541-1192; 64918-1906
Synonyms etonogestrel | 13-ethyl-17-hydroxy-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one | 3-oxodesogestrel | 3-ketodesogestrel | 3-oxo desogestrel | 18,19-dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-11-methylene-, (17-alpha)- | 3-keto-desogestrel | ORG-3236 | Implanon | nexplanon
Chemical Information
Molecular Formula C22H28O2
CAS Registry Number 54048-10-1
SMILES CCC12CC(=C)C3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Polymenorrhagia21.01.03.0040.000825%Not Available
Ligament rupture15.07.02.008; 12.01.07.0140.000825%Not Available
Menstruation normal13.15.01.0450.023510%Not Available
Human chorionic gonadotropin increased13.10.05.0240.000825%Not Available
Infected dermal cyst23.10.02.002; 16.26.02.002; 11.01.12.0240.000825%Not Available
Foetal monitoring abnormal13.21.01.0070.000825%Not Available
Spinal pain17.10.01.020; 15.02.01.008; 08.01.08.0300.001237%Not Available
Invasive ductal breast carcinoma21.05.01.021; 16.10.01.0130.001650%Not Available
Body mass index abnormal13.15.01.0370.002062%Not Available
Skin texture abnormal23.03.03.0680.000825%Not Available
The 19th Page    First    Pre   19    Total 19 Pages